Results 121 to 130 of about 13,668 (163)

Characterization of BioID tagging systems in budding yeast and exploring the interactome of the Ccr4-Not complex. [PDF]

G3 (Bethesda)
Pfannenstein J, Tyryshkin M, Gulden ME, Doud EH, Mosley AL, Reese JC.   +5 more
europepmc   +1 more source

Publisher Correction: Translation efficiency driven by CNOT3 subunit of the CCR4-NOT complex promotes leukemogenesis. [PDF]

Nat Commun
Ghashghaei M, Liu Y, Ettles J, Bombaci G, Ramkumar N, Liu Z, Escano L, Miko SS, Kim Y, Waldron JA, Do K, MacPherson K, Yuen KA, Taibi T, Yue M, Arsalan A, Jin Z, Edin G, Karsan A, Morin GB, Kuchenbauer F, Perna F, Bushell M, Vu LP.   +23 more
europepmc   +1 more source

Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability. [PDF]

RNA Biol, 2020
Mostafa D, Takahashi A, Yanagiya A, Yamaguchi T, Abe T, Kureha T, Kuba K, Kanegae Y, Furuta Y, Yamamoto T, Suzuki T.   +10 more
europepmc   +1 more source

De Novo Variants in CNOT1, a Central Component of the CCR4-NOT Complex Involved in Gene Expression and RNA and Protein Stability, Cause Neurodevelopmental Delay. [PDF]

Am J Hum Genet, 2020
Vissers LELM, Kalvakuri S, de Boer E, Geuer S, Oud M, van Outersterp I, Kwint M, Witmond M, Kersten S, Polla DL, Weijers D, Begtrup A, McWalter K, Ruiz A, Gabau E, Morton JEV, Griffith C, Weiss K, Gamble C, Bartley J, Vernon HJ, Brunet K, Ruivenkamp C, Kant SG, Kruszka P, Larson A, Afenjar A, Billette de Villemeur T, Nugent K, DDD Study, Raymond FL, Venselaar H, Demurger F, Soler-Alfonso C, Li D, Bhoj E, Hayes I, Hamilton NP, Ahmad A, Fisher R, van den Born M, Willems M, Sorlin A, Delanne J, Moutton S, Christophe P, Mau-Them FT, Vitobello A, Goel H, Massingham L, Phornphutkul C, Schwab J, Keren B, Charles P, Vreeburg M, De Simone L, Hoganson G, Iascone M, Milani D, Evenepoel L, Revencu N, Ward DI, Burns K, Krantz I, Raible SE, Murrell JR, Wood K, Cho MT, van Bokhoven H, Muenke M, Kleefstra T, Bodmer R, de Brouwer APM.   +72 more
europepmc   +1 more source

The CCR4-NOT Complex Maintains Stability and Transcription of rRNA Genes by Repressing Antisense Transcripts. [PDF]

Mol Cell Biol, 2019
Hosoyamada S, Sasaki M, Kobayashi T.
europepmc   +1 more source

A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex. [PDF]

Genes Dev, 2019
Keskeny C, Raisch T, Sgromo A, Igreja C, Bhandari D, Weichenrieder O, Izaurralde E.   +6 more
europepmc   +1 more source

The CCR4–NOT complex maintains liver homeostasis through mRNA deadenylation

The CCR4–NOT complex maintains liver homeostasis through mRNA deadenylation
The biological significance of deadenylation in global gene expression is not fully understood. Here, we show that the CCR4-NOT deadenylase complex maintains expression of mRNAs, such as those encoding transcription factors, cell cycle regulators, DNA damage response-related proteins, and metabolic enzymes, at appropriate levels in the liver.
openaire  

Plasmodium male gametocyte development and transmission are critically regulated by the two putative deadenylases of the CAF1/CCR4/NOT complex. [PDF]

PLoS Pathog, 2019
Hart KJ, Oberstaller J, Walker MP, Minns AM, Kennedy MF, Padykula I, Adams JH, Lindner SE.   +7 more
europepmc   +1 more source

Distinct modes of recruitment of the CCR4-NOT complex by Drosophila and vertebrate Nanos. [PDF]

EMBO J, 2016
Raisch T, Bhandari D, Sabath K, Helms S, Valkov E, Weichenrieder O, Izaurralde E.   +6 more
europepmc   +1 more source

Drosophila Bag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets. [PDF]

RNA, 2018
Sgromo A, Raisch T, Backhaus C, Keskeny C, Alva V, Weichenrieder O, Izaurralde E.   +6 more
europepmc   +1 more source