Results 131 to 140 of about 21,976 (228)

Multivalent interactions with CCR4–NOT and PABPC1 determine mRNA repression efficiency by tristetraprolin

Nature Communications
Tristetraprolin family of proteins regulate mRNA stability by binding to specific AU-rich elements in transcripts. This binding promotes the shortening of the mRNA poly(A) tail, or deadenylation, initiating mRNA degradation.
Filip Pekovic, Wi S. Lai, Joshua Corbo, Stephanie N. Hicks, Keiko Luke, Perry J. Blackshear, Eugene Valkov   +6 more
doaj   +1 more source

Th2型趋化因子受体CCR4在原位肝移植急性排斥反应中的表达

Zhongguo shiyan zhenduanxue, 2005
目的　通过检测Th2型趋化因子受体CCR4在移植肝脏急性排斥反应中的表达,探讨Th2型细胞在肝移植急性排斥反应中的作用机制。方法　根据Banff病理分级将原位肝移植术后肝穿刺活检标本分成4组,应用RT -PCR方法半定量分析各组标本中CCR4的mRNA水平。结果　轻度排斥组中11例CCR4高水平表达;中度排斥组中6例、未排斥组中5例CCR4中度水平表达;正常对照组、重度排斥组CCR4均轻度表达。结论　肝移植免疫微环境中CCR4的表达可能与免疫耐受的诱导有关;Th1 ...
孟醒初, 张家颖, 朱志军, 宋燕
doaj  

CCR4 Gene [PDF]

, 2020
openaire   +1 more source

CCR4 wt Allele [PDF]

, 2020
openaire   +1 more source

Thermosensitivity of cellular translation restricts the growth of fission yeast at high temperatures. [PDF]

Commun Biol
Akikusa Y, Yamaguchi A, Funahashi Y, Tan ACW, Mahayot F, Naka T, Matsuo A, Nakase Y, Izawa S, Shiozaki K, Morozumi Y.   +10 more
europepmc   +1 more source

Mogamulizumab for adult T-cell leukemia/lymphoma: a literature review. [PDF]

Transl Cancer Res
Jones C, Wang JC, Saeed H.
europepmc   +1 more source

Engineering fratricide-resistant CCR4/CD7 CAR T cells with enhanced safety and persistence for T cell malignancies. [PDF]

Mol Ther Oncol
Li S, Tu W, Leung W.
europepmc   +1 more source

CCR4 expression defines a targetable subset of T-cell acute lymphoblastic leukemia. [PDF]

Blood Adv
Xu J, McCoy M, Martinez Z, Sussman JH, Gao D, Vincent T, Wang H, Ma C, Elghawy O, Chen GM, Yang AG, Pölönen P, Natan K, Shraim R, Newman H, Hofmann TJ, Scoma S, DiNofia AM, Hunger SP, Yang JJ, Mullighan CG, Bernt KM, Hexner EO, Grupp SA, Watanabe K, June CH, Tan K, Teachey DT, Diorio C.   +28 more
europepmc   +1 more source

CCR4 Inhibitor FLX475 [PDF]

, 2020
openaire   +1 more source

CAR T cells targeting CCR4 selectively deplete human Tregs ex vivo and in vivo. [PDF]

Blood Adv
Tilsed CM, Fong KP, Shi X, Akimova T, Wang L, Noguera-Ortega E, Krouse R, Bermudez A, Singhal S, Young R, Eruslanov E, Watanabe K, Hancock WW, June CH, Albelda SM.   +14 more
europepmc   +1 more source