Results 111 to 120 of about 23,452 (228)

Resolution of Paediatric Cow's Milk Allergy Is Associated With Low Tfh Cell Frequencies and Elevated IL‐17 and IL‐22 Levels

Clinical &Experimental Allergy, EarlyView.
Guillaume Lezmi, Celine Dietrich, Marie‐Alexandra Alyanakian, Messaouda Attailia, Simon Fillatreau, Lucienne Chatenoud, Karine Adel‐Patient, Maria Leite‐de‐Moraes   +7 more
wiley   +1 more source

Graft‐Versus‐Tumour Effect Following Allogeneic Haematopoietic Stem Cell Transplantation in a Paediatric Patient With Mogamulizumab‐Treated Primary Cutaneous Peripheral T‐Cell Lymphoma

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Introduction Primary cutaneous peripheral T‐cell lymphoma, not otherwise specified (pcPTCL‐NOS), is exceptionally rare in children, and evidence guiding diagnosis and treatment is limited. Case Presentation A 10‐year‐old boy with pcPTCL‐NOS refractory to chemotherapy received mogamulizumab prior to allogeneic haematopoietic stem cell ...
Maria Ebbesen Sørum, Tania Masmas, Hilde Uhlving, Lene D. Sjö, Signe Modvig, Hanne V. Marquart, Lone Skov, Lisa Hjalgrim, Marianne Ifversen, Peter Pontoppidan   +9 more
wiley   +1 more source

Psoriatic inflammation enhanced CCR4 and CKLF1 expression by HUVECs.

, 2015
(a) Primary HUVECs exhibited strong factor VIII staining (green) by immunofluorescence. Nuclei were stained by 4',6-diamidino-2-phenylindole (blue). (b) qRT-PCR confirmed elevation of mRNA levels of both CCR4 and CKLF1 upon the addition of psoriatic sera.
Yaqi Tan (730337), Jinyu Xia (730338), Shiguang Peng (730339), Yixuan Wang (643708), Yanling He (364763), Li Li (14993)   +5 more
core   +1 more source

The Microbiome in Glioblastoma: Mechanisms, Tumor–Immune Interactions, and Translational Perspectives

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Proposed microbiome‐related pathways and translational landscape in glioblastoma. Gut dysbiosis may alter microbial metabolites, inflammatory mediators, barrier integrity, immune signaling, and vagal communication, thereby influencing the GBM neuroimmune microenvironment.
Tareq Nayef AlRamadneh, Renuka Jyothi‐S, Priya Priyadarshini‐Nayak, Anima Nanda, Shaker Al‐Hasnaawei, Akanksha Bhatt, Ashish Singh‐Chauhan, Siya Singla, Manoj Kumar Mishra   +8 more
wiley   +1 more source

Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer

MedComm, Volume 7, Issue 10, October 2026.
Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta, Ramakrishna Vadde, Ganji Purnachandra Nagaraju   +2 more
wiley   +1 more source

Distribution of chemokine receptor CCR4⁺CCR6^–, CCR4^–CCR6⁺ and CCR4⁺CCR6⁺ subpopulations of CD4⁺ T lymphocytes.

, 2016
(A) PBMCs were stained with anti-CD4 PE-cy7, anti-CCR4 PE, anti-CCR6 APC and anti-IL-17 FITC. CD4+ T cells were gated for further analysis. (B) The proportion (%) of CCR4+CCR6–/CD4+ T cells (C) CCR4–CCR6+/CD4+ T cells (D) CCR4+CCR6+/CD4+ T cells in each ...
Bo-Mi Kim (314453), Byung Ha Chung (314449), Chul Woo Yang (277266), Kyoung Chan Doh (394391), Mi-La Cho (46882), Kyoung Woon Kim (314451)   +5 more
core   +1 more source

Hypothalamus Participates in Peripheral Sympathetic Hyperactivity After Acute Brain Injury by Regulating Trhr M6A Modification

MedComm, Volume 7, Issue 10, October 2026.
In acute brain injury (TBI/ICH), sympathetic hyperactivity is driven by hypothalamic FTO upregulation. FTO demethylates Trhr, blocking m6A‐YTHDF2‐dependent degradation, which stabilizes Trhr mRNA and increases neuronal sensitivity to TRH. Restoring FTO or Trhr alleviates sympathetic hyperactivity, offering a potential target for managing autonomic ...
Maoxing Fei, Handong Wang, Chaochao Gao, Shiqiao Luo, Xiwen Huang, Yanling Han, Mengliang Zhou, Zhenxing Li   +7 more
wiley   +1 more source

Distinct expression patterns of CCR4 in human gastric cancer.

, 2015
Green fluorescence represents positive cells with membrane and cytoplasmic distribution of CK, red fluorescence represents CCR4-positive cells, whereas yellow represents the merge of both.
Yongmei Yang (331969), Ailin Qu (495673), Xin Zhang (35492), Chengjun Zhou (706302), Lutao Du (332082), Xiaoyun Yang (295189), Chuanxin Wang (332087)   +6 more
core   +1 more source

Mogamulizumab Treatment in a Hemodialysis Patient with Adult T-Cell Leukemia/Lymphoma

Turkish Journal of Hematology, 2014
Mari Yoshihara, Yasushi Kubota, Makoto Fukuda, Tomoya Kishi, Yuji Ikeda, Shinya Kimura   +5 more
doaj   +1 more source

Immune‐Cell Dynamics in the Tumor Microenvironment: Implications for Cancer Therapy

MedComm, Volume 7, Issue 10, October 2026.
Immune‐cell dynamics in the tumor microenvironment converge on four major barriers to effective therapy: failed immune access, defective antigen visibility and priming, loss of effector maintenance, and suppressive tissue remodeling. These barriers emerge from local hypoxic, cytokine, metabolic, and stromal signals.
Pin Guo, Yizhao Xie, Rui Song, Mengdi Yang, Zhen Lin, Chao Guan, Zechen Wang, Jin Wen, Guang‐Liang Chen   +8 more
wiley   +1 more source