Results 121 to 130 of about 34,716 (235)
The role of RNA Polymerase II-dependent transcription elongation in the cross-talk between mRNA synthesis and decay. [PDF]
, 2018 The main molecule in gene expression is messenger RNA (mRNA) which transfers the information contained in genes in the nucleus to the cytoplasm where it is translated into proteins that carry out cellular functions. mRNA levels are determined through its
Begley, Victoria Sarah
core
T Cell Immunosenescence in Inflammatory Skin Diseases: Pathogenesis and Therapeutic Targets
Aging Cell, Volume 25, Issue 5, May 2026.Immunosenescent T cells promote inflammatory skin diseases such as psoriasis, atopic dermatitis, rosacea, and seborrheic dermatitis via hyperactive signaling networks and SASP secretion. Consequently, intercepting downstream SASP, inhibiting internal pathways, or utilizing senolytics represents promising therapeutic interventions.
Conghui Liu +3 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 9, Page 1993-2008, May 2026.Abstract Background and Purpose Immune tolerance prevents inflammation and autoimmunity, with dendritic cells (DCs) playing a key role. Reprogramming DCs towards a tolerogenic state represents a promising therapeutic strategy. Sulforaphane (SFN) has known immunomodulatory effects, but its clinical application is limited by poor stability and ...
María Elena Angarita‐Planchez +6 more
wiley +1 more source
From Development to Aging: Dynamic Roles of the Thymic Medulla in T Cell Biology
Immunological Reviews, Volume 339, Issue 1, May 2026.ABSTRACT The thymic medulla is essential for establishing central tolerance, orchestrating the development of a diverse yet self‐tolerant T cell repertoire, and preventing autoimmunity. This process is primarily mediated through interactions between developing thymocytes and antigen‐presenting cells, including thymic epithelial cells (TECs) and ...
Christina Michalaki +2 more
wiley +1 more source
Mogamulizumab Treatment in a Hemodialysis Patient with Adult T-Cell Leukemia/Lymphoma
Turkish Journal of Hematology, 2014 Mari Yoshihara +5 more
doaj +1 more source
Plant Biotechnology Journal, Volume 24, Issue 5, Page 3106-3124, May 2026.ABSTRACT Plant viruses drive widespread crop epidemics, yet the host plant responses across different cell types, particularly how these responses are influenced by cultivars with varying genetic backgrounds, including the presence of resistance (R) genes, remain poorly understood. Using tomato brown rugose fruit virus (ToBRFV) and two tomato cultivars,
Yuhong Zhang +8 more
wiley +1 more source
The Plant Journal, Volume 126, Issue 3, May 2026.Significance Statement Seed and leaf phenomic traits, including morphology and spectral features, play key roles in consumer preference and plant performance. Here, we conducted a genome‐wide association study of 71 phenomic traits, identifying 73 high‐confidence quantitative trait locus and 114 candidate genes.
Julia von Steimker +14 more
wiley +1 more source
Polymorphism in CCR4 Gene (1014 C/T) in Patients with Breast Carcinoma from the South of Iran
Armaghane Danesh Bimonthly Journal, 2013 Background & aim: CCR4 gene polymorphism at position C/T1014 has been associated with changes in mRNA stability and is involved expression of this molecule.
F Moghaddasi, MR Haghshenas, S Naeimi
doaj
Case Reports in OncologyIntroduction: CC chemokine receptor 4 (CCR4), which is involved in leukocyte migration, is expressed in most tumor cells in patients with adult T-cell leukemia/lymphoma (ATLL).
Masatomo Shimizu +5 more
doaj +1 more source
Cytokines and chemokines in Mycobacterium tuberculosis infection [PDF]
, 2016 Cooper, Andrea +3 more
core +2 more sources