Results 101 to 110 of about 23,452 (228)
Small-Molecule CCR4 Antagonists in Cutaneous T-cell Lymphoma
Mycosis fungoides (MF) and Sézary syndrome (SS) are two most common types of cutaneous T-cell lymphoma (CTCL). Despite advances in understanding the pathogenesis of MF and SS, effective treatments remain limited.
Han, Wei +5 more
core +1 more source
Etiology, pathogenesis and treatment of peri‐implantitis: A European perspective
Periodontology 2000, EarlyView.Abstract Peri‐implantitis is a plaque‐associated pathological condition occurring in tissues around dental implants. It is characterized by inflammation in the peri‐implant mucosa and progressive loss of supporting bone. Over the last 30 years, peri‐implantitis has become a major disease burden in dentistry.
Tord Berglundh +3 more
wiley +1 more source
Algorithms in Allergy: Treatment of Hypereosinophilic Syndromes, 2026 Update
Allergy, EarlyView.
Guillaume Lefèvre +5 more
wiley +1 more source
Translating gut microbiome research into therapies for type 1 diabetes
Experimental Physiology, EarlyView.Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok +2 more
wiley +1 more source
Etude structurale du complexe CCR4-NOT
, 2015 MRNA turnover begins with deadenylation where in the poly(A) tail at the 3’ end of the mRNA is removed. Deadenylation is the rate-limiting step of the decay pathway.
Basquin, Jérôme
core
Composition and function of Ccr4-Not protein complexes [PDF]
, 2010 Ccr4-Not protein complexes are evolutionarily conserved and have important functions in mRNA regulatory processes. Strict regulation of mRNA’s is important for cells since they form the central connection between the genetic information in the nucleus ...
Lau, N.C.
core +1 more source
Comparative ADCC activity of anti-CCR4 antibodies.
, 2014 CCR4-positive CCRF-CEM cells were labeled with calcein and incubated with isolated human PBMCs as effector cells in presence of different concentrations of anti-CCR4 antibodies.
Solène Géraudie (607007) +7 more
core +1 more source
Consumer Cultural Renaissance: Conceptualisation, Scale Development, and Validation
Psychology &Marketing, Volume 43, Issue 11, Page 3178-3189, November 2026.ABSTRACT As incessant globalisation leads to the pervasive erosion of traditional Asian culture by Western consumerism, a recent phenomenon has emerged that allures Asian consumers to reconnect with their traditional culture via consumption. We postulate that this behaviour is rooted in a self‐identity, consumer cultural renaissance (CCR), that has not
Richard Lee +3 more
wiley +1 more source
Annals of Neurology, Volume 100, Issue 4, Page 824-840, October 2026.Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg +33 more
wiley +1 more source
Structural studies of the complex CCR4-NOT
, 2015 Le recyclage des ARN débute par un étape de déadenylation ou la queue poly (A) est enzymatiquement clivée. La deadenylation est l’étape limitante dans le processus de dégradation des ARN.
Basquin, Jérôme
core