Results 21 to 30 of about 4,839 (128)

MULTIPARAMETRIC FLOW CYTOMETRY REFINES RISK STRATIFICATION IN NEWLY DIAGNOSED MULTIPLE MYELOMA PATIENTS

Mediterranean Journal of Hematology and Infectious Diseases, 2023
Multiple myeloma (MM) is a heterogeneous malignancy characterized by the proliferation of abnormal plasma cells in the bone marrow. Multiparametric flow cytometry (MFC) plays a role in the work-up of the disease in view of the aberrant expression of ...
Francesca Fazio, Gianfranco Lapietra, Maria Zaira Limongi, Stefania Intoppa, Maria Laura Milani, Alfonso Piciocchi, Maurizio Martelli, Anna Guarini, Robin Foà, Maria Stefania De Propris, Maria Teresa Petrucci   +10 more
doaj   +1 more source

1,25-Dihydroxyvitamin D3 Stimulates Phagocytosis but Suppresses HLA-DR and CD13 Antigen Expression in Human Mononuclear Phagocytes

Experimental Biology and Medicine, 1996
This study investigated the regulatory activity of 1,25-dihydroxyvitamin D3 (1,25-[OH]2D3) on phagocytic cells obtained from normal human peripheral blood. Flow cytometric analysis enabled identification of two discrete populations of cells, one predominantly monocytes ("monocyte" gate) and one containing primarily lymphoid and other cell types ...
N, Tokuda, R B, Levy
openaire   +2 more sources

The immunoregulatory abilities of polymorphonuclear neutrophils in the course of multiple sclerosis

Mediators of Inflammation, 1998
The polymorphonuclear neutrophils (PMN) possess sufficient potential to affect both immune response and inflammation, however it has not been yet described in the course of multiple sclerosis (MS).
J. Ziaber, J. PaSnik, Z. Baj, L. Pokoca, H. Chmielewski, H. Tchórzewski   +5 more
doaj   +1 more source

Diagnostic Utility of Immunophenotyping by Flow Cytometry for Diagnosis and Classification of Acute Leukemias in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia

Indonesian Journal of Cancer, 2021
Background: Immunophenotypic characterization of acute leukemia is an important clinical application of flow cytometry and has become a powerful tool contributing to proper diagnosis and classification.
Metasebia Tegegen, Fatuma Hassen, Abdulaziz Abubeker, Fissehatsion Tadesse, Daniel Hailu, Ashenafi Alemu, Aster Tsageye, Rawleigh Howe, Amha Gebremedhin   +8 more
doaj   +1 more source

Myeloid antigens in childhood lymphoblastic leukemia:clinical data point to regulation of CD66c distinct from other myeloid antigens

BMC Cancer, 2005
Background Aberrant expression of myeloid antigens (MyAgs) on acute lymphoblastic leukemia (ALL) cells is a well-documented phenomenon, although its regulating mechanisms are unclear. MyAgs in ALL are interpreted e.g.
Madzo Jozef, Mejstrikova Ester, Vaskova Martina, Kalina Tomas, Trka Jan, Stary Jan, Hrusak Ondrej   +6 more
doaj   +1 more source

ACUTE LEUKEMIA OF MIXED B, T AND MYELOID PHENOTYPE WITH COMPLEX KARYOTYPE: TREATABLE DISEASE OR DEATH SENTENCE?

Hematology, Transfusion and Cell Therapy, 2023
The case was attended by our team at Santa Casa de São José dos Campos, a teaching hospital with Accreditation Level 3 from National Accreditation Organization, classified as structuring hospital by the government of the State of São Paulo, which serves ...
DTK Obikawa, LA Vianna, AAM Zung, ES Rosa, F Callera   +4 more
doaj   +1 more source

Identification of APN/CD13 as the target antigen of FU3, a human monoclonal antibody that recognizes malignant fibrous histiocytoma

International Journal of Oncology, 2013
Malignant fibrous histiocytoma (MFH), a high-grade, undifferentiated sarcoma, is highly aggressive, resistant to radiochemotherapy and associated with poor prognosis. There are no specific immunohistochemical markers for its diagnosis. The MFH cell line SFT7913 served as and immunogen for the generation of the FU3 monoclonal antibody in our laboratory.
Mikiko, Aoki, Kazuki, Nabeshima, Hiroyuki, Hayashi, Makoto, Hamasaki, Hiroshi, Iwasaki   +4 more
openaire   +3 more sources

Cannabidiol modulates the immunophenotype and inhibits the activation of the inflammasome in human gingival mesenchymal stem cells

Frontiers in Physiology, 2016
Human Gingival Mesenchymal Stem Cells (hGMSC) are multipotential cells that can expand and differentiate in culture under specific and standardized conditions.
Rosaliana Libro, Domenico Scionti, Francesca Diomede, Marco Marchisio, Gianpaolo Grassi, Federica Pollastro, Adriano Piattelli, Placido Bramanti, EMANUELA MAZZON, Oriana Trubiani   +9 more
doaj   +1 more source

Acute leukemia of childhood: A single institution's experience [PDF]

Archives of Biological Sciences, 2005
The aim of this study was to investigate distribution of immunophenotypic and cytogenetic features of childhood acute leukemia (AL) in the cohort of 239 newly diagnosed patients registered at the leading pediatric oncohematology center in the country ...
Slavković Bojana, Guć-Šćekić Marija, Bunjevački Gordana, Đuričić S., Krstić Aleksandra, Mićić D., Vujić Dragana, Kuzmanović M., Rašović-Gvozdenović Nada   +8 more
doaj   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source