Results 71 to 80 of about 644 (132)

A Novel In‐Cell ELISA With Superior Sensitivity and Specificity for the Detection of African Swine Fever Virus‐Specific IgM and IgG Antibodies

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF), a high‐profile transboundary animal disease caused by ASF virus (ASFV), imposes a devastating impact on the global swine industry. Given that vaccines are still under development, including field evaluations, early detection of ASFV is crucial for effective disease control and mitigation.
Ping Wu   +5 more
wiley   +1 more source

Progress Toward Antigenic Epitopes of African Swine Fever Virus and Their Identification

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
African swine fever virus (ASFV) is a highly contagious pathogen that causes pigs to develop high fever, vomiting, diarrhea, and respiratory distress, with an exceptionally high case fatality rate. Unfortunately, vaccine development is hindered by a limited understanding of the structure and function of the protein encoded by ASFV, as well as the ...
Xingjun Ke   +17 more
wiley   +1 more source

Mitigation Strategies for African Swine Fever Virus Biosecurity: From Virus Inactivation to Pig Health

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
The African swine fever virus (ASFV) is a major global threat affecting pork production and strengthening biosecurity practices is an urgent priority, especially given the paucity of effective vaccines and antiviral drugs. Mitigation strategies focused on virus inactivation play an important role in controlling ASFV and there is growing recognition ...
Joshua A. Jackman   +3 more
wiley   +1 more source

Pathological Characterization of African Swine Fever Viruses With Genetic Deletions Detected in South Korea

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
African swine fever virus (ASFV) genotype II has been circulating in South Korea, causing substantial economic losses to the Korean pig industry since 2019. Genetic epidemiological investigations using whole‐genome sequencing have been conducted to track the genetic evolution of ASFV. Two ASFV strains were detected in domestic pig farms in South Korea,
Seong-Keun Hong   +9 more
wiley   +1 more source

Emergence of Microvariants of African Swine Fever Virus Genotype II in the Asia–Pacific

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
African swine fever virus (ASFV) is a highly stable DNA virus showing little genetic variation among genomes. This genetic stability has often posed challenges in tracking variants and identifying potential transmission chains as ASFV spreads into new regions.
James O’Dwyer   +10 more
wiley   +1 more source

Antiviral Activity of Plant‐Based Additives Against African Swine Fever Virus (ASFV) in Feed Ingredients

open access: yesVeterinary Medicine and Science, Volume 10, Issue 6, November 2024.
Organic acid blend (OAB), a mixture of formic acid, lactic acid, calcium formate, calcium lactate and citric acid, along with Phyto.A04, derived from hops with a CO2 extract from Humulus lupulus flowers, and Phyto.B, containing anhydrous licorice extract (Glycyrrhiza glabra) from aqueous extraction, were tested for their antiviral effects against ...
Thi Ngoc Ha Lai   +8 more
wiley   +1 more source

African swine fever virus E120R inhibited cGAS‐STING‐mediated IFN‐β and NF‐κB pathways

open access: yesAnimal Research and One Health, Volume 2, Issue 1, Page 39-49, February 2024.
ASFV E120R down‐regulated IFN‐β pathway by inhibiting the phosphorylation of STING,TBK1 and IRF3, and suppressed the NF‐κB pathway by inhibiting the nuclear translocation of p50 and p65. Abstract African swine fever (ASF) is an acute and severe contagious disease triggered by the African swine fever virus (ASFV), which severely threatens the global ...
Shuai Cui   +9 more
wiley   +1 more source

Establishment of a Triplex qPCR Assay for Differentiating Highly Virulent Genotype I Recombinant Virus From Low‐Virulence Genotype I and Genotype II African Swine Fever Viruses Circulating in China

open access: yesTransboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
African swine fever virus (ASFV) poses serious threats to the global swine industry, food safety, and the economy. Since August 2018, different types of ASFVs have successively emerged in China, making ASF diagnostics more challenging. The highly virulent genotype I recombinant virus has gradually become the prevalent dominant strain and is identified ...
Leilei Ding   +16 more
wiley   +1 more source

AFRICAN SWINE FEVER VIRUS GLYCOPROTEINS p54 AND CD2v IN THE CONTEXT OF IMMUNE RESPONSE MODULATION: BIOINFORMATIC ANALYSIS OF GENETIC VARIABILITY AND HETEROGENEITY [PDF]

open access: yesSel'skokhozyaistvennaya Biologiya, 2015
The African swine fever virus (ASFV) is a unique representative of Asfaviridae family, which still remains the sole member of genus Asfarvirus. ASF virus is the causative agent of one of the most dangerous diseases of the animals from Suidae family, and moreover, it is capable of infecting soft ticks of the genus Ornithodoros.
K.A. MIMA   +3 more
openaire   +2 more sources

When ASFV Infection Meets the cGAS‐STING Signaling Pathway

open access: yesTransboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
The African swine fever virus (ASFV) has the ability to infect both wild boars and domestic pigs, regardless of their breeds or ages, often resulting in a mortality rate of 100%. Host innate immunity is the most important defense weapon against invasion of pathogenic microbial infection.
Songbiao Chen   +7 more
wiley   +1 more source

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