Results 81 to 90 of about 153 (95)

Pathogenetic mechanisms of ASFV–host immune system interaction and their implications for epizootiology and livestock biosecurity [PDF]

Науковий вісник ветеринарної медицини
African Swine Fever (ASF) is a highly contagious transboundary viral disease that causes significant economic losses and poses a threat to global biosecurity.
Romanishina Т., Lakhman A., Galatiuk O., Behas V.   +3 more
doaj   +1 more source

A triple protein-based ELISA for differential detection of ASFV antibodies

Frontiers in Veterinary Science
African swine fever (ASF) caused by the ASF virus (ASFV) is a severe and highly contagious viral disease that poses a significant threat to the global pig industry.
Shuai Zhang, Yuzhu Zuo, Wenyuan Gu, Yunhuan Zhao, Ying Liu, Jinghui Fan, Jinghui Fan   +6 more
doaj   +1 more source

Nanobodies against African swine fever virus p72 and CD2v proteins as reagents for developing two cELISAs to detect viral antibodies

Virologica Sinica
African swine fever virus (ASFV) poses a significant threat to the global swine industry. Currently, there are no effective vaccines or treatments available to combat ASFV infection in pigs. The primary means of controlling the spread of the disease is through rapid detection and subsequent elimination of infected pig.
Jiahong Zhu, Qingyuan Liu, Liuya Li, Runyu Zhang, Yueting Chang, Jiakai Zhao, Siyu Liu, Xinyu Zhao, Xu Chen, Yani Sun, Qin Zhao   +10 more
openaire   +2 more sources

Development and efficacy of a novel mRNA cocktail for the delivery of African swine fever virus antigens and induction of immune responses

Microbiology Spectrum
African swine fever (ASF) is a highly lethal infectious disease affecting pigs. Although several vaccine formulations have been developed to protect from ASF virus (ASFV) infection, none have yet provided complete protection without side effects or the ...
Xing Hu, Cong Liu, Nino Rcheulishvili, Yunzhi Wang, Ting Xiong, Fengfei Xie, Xingyun Wang, Ruiai Chen, Peng George Wang, Yunjiao He   +9 more
doaj   +1 more source

A Pool of Ferritin Nanoparticles Delivering Six Proteins of African Swine Fever Virus Induces Robust Humoral and Cellular Immune Responses in Pigs

Vaccines
Background/Objectives: Inadequate characterization of protective antigens poses a significant challenge to the development of vaccines for African swine fever (ASF), particularly for antigen-dependent formulations such as subunit, mRNA, and recombinant ...
Zhanhao Lu, Dailang Zhong, Xin Song, Jing Lan, Yanjin Wang, Rui Luo, Shengmei Chen, Ruojia Huang, Hua-Ji Qiu, Yongfeng Li, Tao Wang, Yuan Sun   +11 more
doaj   +1 more source

Modulation of MHC class I expression by African swine fever virus and the role of virus proteins EP153R and CD2v

, 2014
Various DNA viruses, including pox- and herpesviruses, express proteins which down-regulate host MHC class I antigen expression as an immune evasion strategy. Previous studies into whether ASFV modulates expression of the porcine MHC class I molecule, SLA I, have not provided a clear answer. In this thesis, the effect of African swine fever virus (ASFV)
openaire   +3 more sources

Modulation of MHC class I expression by African swine fever virus and the role of virus proteins EP153R and CD2v

, 2016
Various DNA viruses, including pox- and herpesviruses, express proteins which downregulate host MHC class I antigen expression as an immune evasion strategy. Previous studies into whether ASFV modulates expression of the porcine MHC class I molecule, SLA-I, have not provided a clear answer. In this thesis, the effect of African swine fever virus (ASFV)
openaire   +1 more source

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Development and characterization of recombinant ASFV CD2v protein nanoparticle-induced monoclonal antibody

International Journal of Biological Macromolecules, 2022
African swine fever (ASF) caused by African swine fever virus (ASFV) is becoming a serious threat to the swine industry worldwide. CD2v is a key pathogenic factor of ASFV and the protective antigen with low immunogenicity, whereas viral protein-based nanoparticles have advantages of precise assembly and high immunogenicity.
Dongna, Ren, Peiyang, Ding, Siyuan, Liu, Ning, Zhang, Yilan, Chen, Qingmei, Li, Lu, Fan, Zejie, Chang, Gaiping, Zhang   +8 more
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Genetic analysis of African swine fever virus in Bali based on p72 and CD2v Genes

International Journal of Science and Technology Research Archive
African Swine Fever (ASF) has caused negative effects in the swine industry in various countries of the world, including Indonesia. Bali is one of the most severely affected provinces in Indonesia. Phylogenetic study to determine the genotype and serogroup of the ASF virus found in Bali has never been done before. In this study, virus was obtained from
null Putu Andarisa Widyastiti, null I Gusti Ngurah Kade Mahardika, null Ida Bagus Kade Suardana   +2 more
openaire   +1 more source

A plant-based oligomeric CD2v extracellular domain antigen exhibits equivalent immunogenicity to the live attenuated vaccine ASFV-G-∆I177L

Medical Microbiology and Immunology
African swine fever (ASF), caused by the African swine fever virus (ASFV), is a deadly, highly contagious disease in both domestic pigs and wild boar. With mortality up to 100%, the disease has been making a serious impact on the swine industry worldwide.
Giang Thu Nguyen, Thanh Thi Le, Son Duy Thai Vu, Tra Thi Nguyen, My Thi Tra Le, Van Thi Pham, Hien Thi Thu Nguyen, Thuong Thi Ho, Hang Thi Thu Hoang, Hanh Xuan Tran, Ha Hoang Chu, Ngoc Bich Pham   +11 more
openaire   +2 more sources