Results 111 to 120 of about 33,325 (191)
Guiding the Application of Immunotherapy in Nonsmall Cell Lung Cancer: The Role of Biomarkers
Thoracic Cancer, Volume 17, Issue 18, September 2026.The content is divided into three main parts: (1) Predictive biomarkers: this includes six detailed subcategories. (2) Prediction of immune resistance: Lists relevant cell and gene markers. (3) Prediction of immune‐related adverse reactions. ABSTRACT Although immunotherapy has completely transformed the treatment landscape of nonsmall cell lung cancer (
Yuting Sun +8 more
wiley +1 more source
Integrated Engineering of CAR‐T Cells for Solid Tumours
Cell Proliferation, Volume 59, Issue 9, September 2026.Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang +5 more
wiley +1 more source
Pain Practice, Volume 26, Issue 7, September 2026.ABSTRACT Background Several studies point towards the involvement of the immune system (especially the monocyte–macrophage system) in the pathophysiology of Complex Regional Pain Syndrome (CRPS), as shown by increased levels of the cytokines tumor necrosis factor (TNF)‐α and interleukin (IL)‐6.
Nadia Kriek +6 more
wiley +1 more source
CD39 dynamics in tuberculosis: a potential biomarker of immune dysregulation and T cell exhaustion
Frontiers in ImmunologyBackgroundTuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a global health crisis complicated by immune dysregulation and T cell exhaustion.
Ling Hao +3 more
doaj +1 more source
Xenotransplantation, Volume 33, Issue 5, September/October 2026.ABSTRACT Lung transplantation is the only long‐lasting life‐saving treatment for patients with end‐stage pulmonary disease, but the ever‐growing shortage of suitable donor organs leads to high mortality rates of the afflicted patients. Xenotransplantation, the transplantation of organs across species, has emerged as a promising alternative. This review
Nathalie Roters +6 more
wiley +1 more source
CD25 and CD39 expression in CD4+ T cells.
, 2013 Compare results from HAM/TSP patients, HTLV-1 asymptomatic carriers (AC) and uninfected subjects.
Harry Wynn-Williams (280357) +10 more
core +1 more source
Cancer immunotherapy by adenosinergic CD39 and CD73 as emerging immune checkpoints
Discover OncologyExtracellular adenosine has recently been identified as an immunological checkpoint mediator that hinders the immune response to malignancies. The production of adenosine is facilitated by the enzymatic activity of CD39 and CD73.
Xinyu Yin, Ying Yang, Songjiang Liu
doaj +1 more source
Heart failure‐induced reprogramming of salt‐evoked neurovascular coupling in the rat hypothalamus
The Journal of Physiology, Volume 604, Issue 18, Page 7845-7868, 15 September 2026.Abstract figure legend In sham rat, hypertonic saline induces activation of the AVP neurons, leading to dendritic AVP release and subsequent V1aR‐mediated PA vasoconstriction resulting in local tissue hypoxia in the SON. In heart failure rat, hypertonic saline similarly induces activation of the AVP neuron leading to dendritic AVP release.
Ranjan K. Roy +4 more
wiley +1 more source
Treg inhibit IL-2 production via the CD39 pathway.
, 2013 (A) Using CD39 cell surface expression, Treg/CD39+ and Treg/CD39− were sorted and co-cultured with CFSE labeled CD4+CD45RA+CD25low naive T cells (ratio ½).
Ayrin Kök (214658) +12 more
core +1 more source
International Journal of NanomedicineXiaoshan Yang,1– 3,* Yang Zhou,2,3,* Fuxing Zhou,4,* Lili Bao,2,3 Zhengyan Wang,5 Zihan Li,2,3 Feng Ding,2,3 Huijuan Kuang,6,7 Huan Liu,8 Shenglong Tan,1 Xinyuan Qiu,1 Huan Jing,9 Shiyu Liu,2,3 Dandan Ma1 1Department of Endodontics ...
Yang X +13 more
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