Results 121 to 130 of about 31,390 (228)

High‐Dimensional Immune Profiling Identifies Circulating NKT‐Like Cells Associated With Severity Outcome in Acute Pancreatitis at Disease Onset

Immunology, Volume 178, Issue 4, Page 685-703, August 2026.
High‐dimensional spectral cytometry of peripheral blood mononuclear cells at hospital admission revealed that acute pancreatitis patients who subsequently developed moderately‐to‐severe disease exhibited a specific reduction of circulating CD2 + CD8dim NKT‐like cells, which appear to acquire an altered cytotoxic‐like phenotype upon IL‐15 stimulation ...
Carolina González de Castro, Mª. Lourdes Ruiz Rebollo, Paloma Cal‐Sabater, Elisa Arribas‐Rodríguez, Álvaro Martín‐Muñoz, Alejandro Gonzalez del Hierro, Marina Perez Mazzali, Jessica Matesanz‐Isabel, Hugo Gonzalo‐Benito, Sara Cuesta‐Sancho, David Bernardo   +10 more
wiley   +1 more source

Variable impact of CD39 in experimental murine colitis [PDF]

, 2011
Background: Dysregulation of immune responses in inflammatory bowel diseases (IBD) results in intestinal inflammation and vascular injury while exacerbating systemic disease.
SC Robson (14541245), BM Künzli (14541395), K Enjyoji (13612147), PO Berberat (14541404), G Moore (7691351), H Friess (13612597), E Csizmadia (13612591), P Cowan (2892578), S Deaglio (13612099), A D'Apice (13612594), K Dwyer (14541254)   +10 more
core  

CD39 activity correlates with stage and inhibits platelet reactivity in chronic lymphocytic leukemia

Journal of Translational Medicine, 2007
Background Chronic lymphocytic leukemia (CLL) is characterized by accumulation of mature appearing lymphocytes and is rarely complicated by thrombosis. One possible explanation for the paucity of thrombotic events in these patients may be the presence of
Islam Naziba, Broekman M Johan, Olson Kim E, Pulte Dianne, Ballard Harold S, Furman Richard R, Olson Ashley E, Marcus Aaron J   +7 more
doaj   +1 more source

Transcriptional analysis of CD39⁺ and CD39^– CD8⁺ T cells in HCV infection. [PDF]

, 2015
(A) Consensus hierarchical clustering of expression profiles from CD39+ (black) and CD39– (grey) CD8+ T cells from 8 HCV infected patients. Clustering is based on the top 10% of genes by variance across the dataset.
Jernej Godec (816310), W. Nicholas Haining (154505), Wolfgang G. Junger (397608), E. John Wherry (212944), Paul Klenerman (33807), Cormac Cosgrove (358780), Galit Alter (91383), Prakash K. Gupta (816309), Simon C. Robson (301209), Philip J. R. Goulder (83293), Carola Ledderose (355829), David Wolski (5665549), Kathleen Yates (816311), Kristen E. Pauken (816312), Arlene H. Sharpe (154508), Georg M. Lauer (620394), Emily Adland (452953)   +16 more
core   +1 more source

NTPDase1/CD39 and aberrant purinergic signalling in the pathogenesis of COPD [PDF]

, 2016
Purinergic receptor activation via extracellular ATP is involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). Nucleoside triphosphate diphosphohydrolase-1/CD39 hydrolyses extracellular ATP and modulates P2 receptor signalling.We ...
Robson, Simon C., Idzko, Marco, De Cunto, G, Hossfeld, Madelon, Robson, SC, Mullner, N, Meyer, A, Müllner, Nina, Cunto, Giovanna De, Yegutkin, Gennady G., Sorichter, Stephan, Meyer, Anja, DE CUNTO, GIOVANNA, Cicko, S, Idzko, M, Hossfeld, M, Lungarella, G, Virchow, Christian J., LUNGARELLA, GIUSEPPE, Muller, T, Lazar, Zsofia, Virchow, Johann Christian, Lucattelli, M, Yegutkin, GG, LUCATTELLI, MONICA, Sorichter, S, Ayata, Korcan, Ayata, Cemil Korcan, Horvath, Ildiko, Müller, Tobias, Virchow, CJ, Cicko, Sanja, Ayata, CK   +32 more
core   +1 more source

CD39-Diannexin alleviates the platelet storage lesion by protecting platelets from activation, a new attempt from a traditional perspective

Platelets
Due to platelet storage lesions (PSL), transfused platelets are unable to function properly in the prevention and treatment of bleeding in critically ill patients.
Cheng Liu, Peng Wang, Yafei Gao, Xiaolong Ma, Yang Su, Yao Wei, Rui Qiao   +6 more
doaj   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

RanBPM associates with CD39 and modulates ecto-nucleotidase activity [PDF]

, 2006
CD39/ecto-NTPDase 1 (nucleoside triphosphate diphosphohydrolase 1) is an ecto-nucleotidase that influences P2 receptor activation to regulate vascular and immune cell adhesion and signalling events pivotal in inflammation.
Y Wu (808222), SC Robson (14541245), A Usheva (13612159), KM Dwyer (14448135), X Sun (6794357), E Bianchi (13612156), E Kaczmarek (13612153)   +6 more
core  

CD39 and CD73: biological functions, diseases and therapy

Molecular Biomedicine
Abstract Cluster of differentiation 39 (CD39) and CD73 are ectonucleotidases that play pivotal roles in purinergic signaling. CD39 catalyzes the hydrolysis of adenosine triphosphate (ATP) to adenosine diphosphate (ADP) and subsequently to adenosine monophosphate (AMP), while CD73 further catalyzes the hydrolysis of AMP to adenosine ...
Jie Shen, Bin Liao, Li Gong, Sha Li, Juan Zhao, Huiyao Yang, Yi Gong, Yongsheng Li   +7 more
openaire   +2 more sources

CD39 dynamics in tuberculosis: a potential biomarker of immune dysregulation and T cell exhaustion

Frontiers in Immunology
BackgroundTuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a global health crisis complicated by immune dysregulation and T cell exhaustion.
Ling Hao, Ling Hao, Qari Muhammad Imran, Nadeem Ullah   +3 more
doaj   +1 more source