Serum CD73 activity as a biomarker of hypoxemia in COVID-19 patients. [PDF]
Le Borgne P +10 more
europepmc +1 more source
Small Subset, Big Impact: Regulatory Function of γδ T Cells in Arteriogenesis. [PDF]
Wimmer KS +9 more
europepmc +1 more source
CD39 polymorphism enables lung thrombosis in sickle cell disease. [PDF]
Brzoska T +26 more
europepmc +1 more source
CD39<sup>+</sup>PD-1<sup>+</sup> regulatory T cells in melanoma: key drivers of systemic immunosuppression and prognostic biomarkers. [PDF]
Qiao G, He H, Wang X.
europepmc +1 more source
Nucleotide signaling in neutrophils: a key player in cancer dynamics. [PDF]
da Silva JLG, Sévigny J, Leal DBR.
europepmc +1 more source
SNP rs10748643 determines CD39 expression in T and NK cells through altering NFIC binding affinity rather than interfering with RNA splicing. [PDF]
Gan C +6 more
europepmc +1 more source
Resistance exercise exerts anti-hypertensive effects and downregulates NTPDase/CD39 and ecto-5'-nucleotidase/CD73 expression in patients with chronic kidney disease undergoing hemodialysis. [PDF]
Dalagnol AMK +7 more
europepmc +1 more source
CD39 and control of cellular immune responses [PDF]
CD39 is the cell surface-located prototypic member of the ecto-nucleoside triphosphate diphosphohydrolase (E-NTPDase) family. Biological actions of CD39 are a consequence (at least in part) of the regulated phosphohydrolytic activity on extracellular nucleotides.
Simon C Robson +2 more
exaly +14 more sources
CD39 Regulation and Functions in T Cells [PDF]
CD39 is an enzyme which is responsible, together with CD73, for a cascade converting adenosine triphosphate into adenosine diphosphate and cyclic adenosine monophosphate, ultimately leading to the release of an immunosuppressive form of adenosine in the tumor microenvironment.
Vincenzo Barnaba +2 more
exaly +7 more sources
Implications of CD39 in immune-related diseases
Extracellular adenosine triphosphate (eATP) mediates pro-inflammatory responses by recruiting and activating inflammatory cells. CD39 can hydrolyze eATP into adenosine monophosphate (AMP), while CD73 can convert AMP into the immunosuppressive nucleoside adenosine (ADO).
Chunxia Li
exaly +3 more sources

