Results 191 to 200 of about 34,165 (229)
Some of the next articles are maybe not open access.
Development of CD39 as a therapy for stroke
2022The brain is detrimentally affected after stroke and cardiac arrest. The aim of this thesis was to demonstrate that the novel drug from our lab - αVCAM-CD39 will improve neurological outcome in mouse models of stroke and cardiac arrest. We found that post- αVCAM-CD39 treatment, there was significant protection in the brain, and we showed that our ...
openaire +1 more source
Preservation of cochlear function in Cd39 deficient mice
Hearing Research, 2009Signalling actions of extracellular nucleotides via P2 receptors influence cellular function in most tissues. In the inner ear, P2 receptor signaling is involved in many processes including the regulation of hearing sensitivity and the cochlea's response to noise stress.
Srdjan M, Vlajkovic +7 more
openaire +2 more sources
The skinny on CD39 in immunity and inflammation
Nature Medicine, 2002The finding that CD39 on Langerhans cells modulates inflammation and immunity in the skin might lead to new strategies to alter immune responses to benefit patients and suggests a new in vitro technique for assessing the irritant potential of topical agents. ( pages 358–365 )
openaire +1 more source
A2AR Limits IL-15-Induced Generation of CD39+ NK Cells With High Cytotoxicity
International Immunopharmacology, 2023Jingjing Cong, Xueqin Zhao, Guijie Kang
exaly
Novel Modulators of CD39 and CD73
CD39 and CD73 are crucial in purinergic signalling, converting triphosphate and diphosphate nucleotides such as ATP and ADP into AMP, which CD73 further degrades into adenosine. CD39 and CD73 dysregulation is linked to various diseases. In cancer, their upregulation is associated with immune suppression, while downregulation in autoimmune disorders ...openaire +1 more source
CD39 Expression in Mesenchymal Stromal Cells
Journal of Immunotherapy, 2011Felipe, Saldanha-Araujo +1 more
openaire +2 more sources