Results 31 to 40 of about 31,390 (228)

CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation [PDF]

, 2008
Plasma microparticles (MPs,
Beldi, Guido, Wu, Yan, Robson, Simon C, Banz, Yara, Atkinson, Ben, Usheva, Anny   +5 more
core   +1 more source

Features of parameters of cellular immune depending on the activity of foci of demyelination in children with multiple sclerosis

Медицинская иммунология, 2023
MS is a common disease of the central nervous system that leads to disability and reduced quality of life. The debut of disease in 3-5% of patients occurs in childhood and has a less favorable course compared to adults.
T. V. Radygina, D. G. Kuptsova, O. V. Kurbatova, S. V. Petrichuk, E. L. Semikina, A. P. Fisenko, L. M. Abdullaeva, B. I. Bursagova   +7 more
doaj   +1 more source

CD39/Adenosine Pathway Is Involved in AIDS Progression [PDF]

PLoS Pathogens, 2011
HIV-1 infection is characterized by a chronic activation of the immune system and suppressed function of T lymphocytes. Regulatory CD4+ CD25(high) FoxP3+CD127(low) T cells (Treg) play a key role in both conditions. Here, we show that HIV-1 positive patients have a significant increase of Treg-associated expression of CD39/ENTPD1, an ectoenzyme which in
Nikolova, Maria, Carriere, Matthieu, Jenabian, Mohammad-Ali, Limou, Sophie, Younas, Mehwish, Kök, Ayrin, Huë, Sophie, Seddiki, Nabila, Hulin, Anne, Delaneau, Olivier, Schuitemaker, Hanneke, Herbeck, Joshua, Mullins, James, Muhtarova, Maria, Bensussan, Armand, Zagury, Jean-François, Lelievre, Jean-Daniel, Lévy, Yves   +17 more
openaire   +8 more sources

Regulated catalysis of extracellular nucleotides by vascular CD39/ENTPD1 is required for liver regeneration [PDF]

, 2008
BACKGROUND & AIMS: Little is known about how endothelial cells respond to injury, regulate hepatocyte turnover and reconstitute the hepatic vasculature.
Enjyoji, K, Erb, L, Imai, M, Csizmadia, E, Wu, Y, Beldi, G, Sun, X, Robson, S.C., Candinas, D   +8 more
core   +1 more source

Impact of CD39 and purinergic signalling on the growth and metastasis of colorectal cancer [PDF]

, 2011
Despite improvements in prevention and management of colorectal cancer (CRC), uncontrolled tumor growth with metastatic spread to distant organs remains an important clinical concern.
Robson, Simon C., Simon C. Robson, Maria-Isabell Bernlochner, Käser, Samuel, Dwyer, Karen, Maurer, Christoph A., Samuel Käser, Csizmadia, Eva, Rath, Stephan, Beat M. Künzli, Robson, Simon C, Helmut Friess, Aurel Perren, Cowan, Peter, Perren, Aurel, Rosenberg, Robert, Enjyoji, Keiichi, Stephan Rath, Christoph A. Maurer, Künzli, Beat M., Bernlochner, Maria-Isabell, Friess, Helmut, Keiichi Enjyoji, Eva Csizmadia, d'Apice, Anthony, Peter Cowan, Robert Rosenberg, Anthony d’Apice, Maurer, Christoph A, Karen Dwyer, Künzli, Beat M   +30 more
core   +1 more source

Reduced Ki67 expression in CD4⁺CD39⁺ T cells following CD39 blocking. [PDF]

, 2018
PBMC from microfilaremic (Fil+) and uninfected (Fil-) subjects were stained for intracellular Ki67, an indicator of T-cell proliferation. We first compared the proportion of Ki67+ cells among CD4+CD39+ and CD4+CD39- T cells (panel A) and CD39+ and CD39 ...
Marcelo U. Ferreira (138475), Raquel M. Gonçalves-Lopes (4288384), Nathália F. Lima (622805), Maria Yazdanbakhsh (90295), Yvonne C. M. Kruize (90288)   +4 more
core   +1 more source

Host CD39 Deficiency Affects Radiation-Induced Tumor Growth Delay and Aggravates Radiation-Induced Normal Tissue Toxicity

Frontiers in Oncology, 2020
The ectonucleoside triphosphate diphosphohydrolase (CD39)/5′ ectonuclotidase (CD73)-dependent purinergic pathway emerges as promising cancer target. Yet, except for own previous work revealing a pathogenic role of CD73 and adenosine in radiation-induced ...
Alina V. Meyer, Diana Klein, Simone de Leve, Klaudia Szymonowicz, Martin Stuschke, Simon C. Robson, Verena Jendrossek, Florian Wirsdörfer   +7 more
doaj   +1 more source

A gut feeling for CD39 [PDF]

Science-Business eXchange, 2009
American and German researchers have reported that enhancing CD39 activity in the gut could help treat inflammatory bowel disease. The researchers are now developing a soluble form of CD39 that they hope could become an infusible therapeutic to treat colitis and Crohn's disease.
openaire   +1 more source

Rat pancreas secretes particulate ecto-nucleotidase CD39 [PDF]

, 2003
Udgivelsesdato: 2003-Sep-15In exocrine pancreas, acini release ATP and the excurrent ducts express several types of purinergic P2 receptors. Thereby, ATP, or its hydrolytic products, might play a role as a paracrine regulator between acini and ducts. The
Ankorina-Stark, Ieva, Amstrup, Jan, Rasmussen, Hans N, Novak, Ivana, Sørensen, Christiane Elisabeth   +4 more
core   +1 more source

Development of aortic endothelial cells to express CD37 and CD73 isolated from alpha 1,3-galactosyltransferase knock-out and MCP expressing pig

Journal of Animal Reproduction and Biotechnology, 2018
Acute vascular rejection has been known as a main barrier occurring in a xenograted tissue of alpha 1,3-galactosyltransferase knock-out (GalT KO) pig into a non-human primate (NHP). Adenosine which is a final metabolite following sequential hydrolysis of
Jin-Gu No, Sung-June Byun, Hyeon Yang, Sun A Ock, Jae-Seok Woo, Hwi-Cheul Lee, In-sul Hwang, Ji-Youn Kim, Sang Hyoun Park, Joo Young Lee, Keon Bong Oh   +10 more
doaj   +1 more source