Results 101 to 110 of about 38,316 (246)

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Reduced expression of monocyte CD200R is associated with enhanced proinflammatory cytokine production in sarcoidosis [PDF]

, 2016
In sarcoidosis, the proinflammatory cytokines interferon gamma, tumour necrosis factor and interleukin-6 are released by monocyte-derived macrophages and lymphocytes in the lungs and other affected tissues. Regulatory receptors expressed on monocytes and
A Crawshaw, AD Vorselaars, AS Bansal, C Prior, CI Daïen, D De Groote, D Hijdra, D Lecossier, DG Walker, DR Moller, GJ Friou, GJ Gibson, GJ Wright, H Fehrenbach, HM Cherwinski, J Baran, J Carlisle, J Unitt, JC Grutters, JP Utz, K Lindahl-Kiessling, K Sahashi, KW Moore, L Landsman, L Ziegler-Heitbrock, M Steffen, MC Jenmalm, MP Chao, O Selroos, P Rottoli, R Gorczynski, RJ Snelgrove, RM Gorczynski, RP Baughman, RP Baughman, S Gao, S Gilbert, SA Eming, SL Kunkel, T Hussell, Y Li   +40 more
core   +2 more sources

CD47 Expression on breast cancer cell-lines

, 2021
Κωνσταντίνος Τσομακιάν
openalex   +1 more source

Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases

ChemistryEurope, EarlyView.
Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang, Jinxia Wang, Guang‐Zhi Jin, István Bányai, Dzmitry Shcharbin, Ivan Stoikov, Mingwu Shen, Xiangyang Shi   +7 more
wiley   +1 more source

Crossing the Vascular Wall: Common and Unique Mechanisms Exploited by Different Leukocyte Subsets during Extravasation [PDF]

, 2015
Leukocyte extravasation is one of the essential and first steps during the initiation of inflammation. Therefore, a better understanding of the key molecules that regulate this process may help to develop novel therapeutics for treatment of inflammation ...
Alcaide, P, Schnoor, M, van Buul, JD, Voisin, M-B   +3 more
core   +5 more sources

HIV-1 Vpu promotes phagocytosis of infected CD4 ⁺ T cells by macrophages through downregulation of CD47 [PDF]

, 2021
Lijun Cong, Scott Sugden, Pascal Leclair, Chinten James Lim, Tram N. Q. Pham, Éric A. Cohen   +5 more
openalex   +1 more source

Advanced extracellular vesicle immunotherapy

FlexMat, EarlyView.
A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang, Yunfei Mu, Xianyue Ji, Xiaoting Jiang, Ruiheng Wang, Xianguang Ding, Lianhui Wang   +6 more
wiley   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

Effect and mechanism of targeted delivery of VEGF and CD47 dual-modifiedexosomes in treatment of acute kidney injury induced by heat stroke in rats in the desert dry hot environment.

陆军军医大学学报
Objective To develop an effective method for delivering VEGF and CD47 double-modified exosomes to treat renal damage induced by heat stroke so as to reduce and repair renal damage.
HAN Xiaobo, DENG Xinkai, LI Hong
doaj   +1 more source

Combined prognostic value of the cancer stem cell markers CD47 and CD133 in esophageal squamous cell carcinoma

Cancer Medicine, 2019
Background Treatments based on the inhibition of pivotal signals of cancer stem cells (CSCs) are on a promising track. Recent studies have shown that targeting CSCs with broader immune‐based therapeutic methods, for example, the anti‐CD47 treatment, may ...
Jian‐Hua Wang, Shu‐Ting Huang, Lan Zhang, Zi‐Gang Liu, Rong‐Xin Liang, Sen‐Wei Jiang, Yi‐Nan Jiang, Xing‐Juan Yu, Yu‐Chuan Jiang, Xi‐Zhao Li, Pei‐Fen Zhang, Zhe‐Sheng Wen, Min Zheng   +12 more
doaj   +1 more source