Results 61 to 70 of about 88,420 (193)
Distinct effects of CD86-mediated costimulation on resting versus activated human CD4(+) T cells
, 2005 CD80 and CD86 are important in the initiation of T cell immunity. Although their costimulatory function has long been appreciated, it remains unclear whether the biological significance of the two B7 isoforms resides in their different patterns and ...
Rogers, N J +11 more
core +1 more source
The CD86 expression on B cells cultured with T. halophilus.
, 2018 The spleen B220+ cells prepared from C57BL/6 mouse spleen were cultured with 1 μg of T. halophilus strains in 1 mL of PRMI1640 medium containing 10% FCS for 2 days. The cells were collected and stained with anti-B220 mAb and anti-CD86 mAb.
Atsuhisa Nishimura (6156719) +3 more
core +1 more source
, 1998 Atopic allergic asthma is characterized by activation of Th2-type T cells in the bronchial mucosa. Previous reports have suggested an important role for costimulation through the CD28/CTLA4-CD80/CD86 pathway in allergen activation of T cells in animal ...
Haselden, B M +7 more
core +2 more sources
CD86 is an activation receptor for NK cell cytotoxicity against tumor cells.
PLoS ONE, 2013 CTLA4Ig has been successfully used in the clinic for suppression of T cell activation. However, patients treated with CTLA4Ig experienced reduced incidence of tumors than predicted, but the underlying mechanism remains unknown.
Yanmeng Peng +12 more
doaj +1 more source
CD86 has sustained costimulatory effects on CD8 T cells
, 2007 CD80 and CD86 both costimulate T cell activation. Their individual effects in vivo are difficult to study as they are coordinately up-regulated on APCs. We have studied mice expressing rat insulin promoter (RIP)-CD80 and RIP-CD86 on the NOD and NOD.scid ...
Guerder, S +8 more
core
The surface expression of CD83, CD80, CD86, and HLA-DR of infected MoDCs.
, 2023 The surface expression of CD83, CD80, CD86, and HLA-DR of infected MoDCs.
Pratomporn Krangvichian (12880346) +6 more
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CD86+ B cells are more frequent in HIV+ than HIV- subjects and correlate with viremia.
, 2013 PBMCs from HIV- (open circles) or HIV+ (closed circles) subjects were incubated overnight without stimulation and evaluated for surface level CD86 expression on B cells.
Louise Barnett (264790) +7 more
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CD86 expression at the nasal mucosa.
, 2013 After intervention, the percentages of CD86+ Cytokeratin+ epithelial (A) and CD86+ CD252+ non-epithelial (B) cells are compared at baseline between control (C0) and treatment (T0) groups and then again 24 hours after nasal allergen challenge (C24, T24); (
Marta Westwood (485655) +9 more
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Parasites & Vectors, 2010 Background Tick parasitism is a major impediment for cattle production in many parts of the world. The southern cattle tick, Rhipicephalus (Boophilus) microplus, is an obligate hematophagous parasite of domestic and wild animals that serves as vector of ...
Tidwell Jason P +3 more
doaj +1 more source
Immunomodulatory molecules in renal cell cancer: CD80 and CD86 are expressed on tumor cells [PDF]
, 2017 Despite modern therapies with tyrosine kinase inhibitors (TKI), the management of patients with metastatic renal cell carcinoma (mRCC) remains a challenge. Significant immunosuppression has been described in patients with mRCC.
Flörcken, A. +8 more
core +1 more source