Results 151 to 160 of about 69,053 (332)
Resetting a functional G1 nucleus after mitosis [PDF]
, 2016 © The Author(s) 2015. The maintenance of the correct cellular information goes beyond the simple transmission of an intact genetic code from one generation to the next. Epigenetic changes, topological cues and correct protein-protein interactions need to
De Castro, IJ, Gokhan, E, Vagnarelli, P
core +2 more sources
Advanced Science, EarlyView.This study reveals a new mechanism by which PDIA3P1 regulates the progression of esophageal squamous cell carcinoma (ESCC). PDIA3P1 upregulates the expression of GLUT1 and HK2, promoting glycolysis and lactate production. Lactate upregulates the lactylation level of histone H4K8 and activates the transcription of target gene BMP7, ultimately ...
Tao Huang +13 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies STAU2 as an oncogenic RNA‐binding protein (RBP) with elevated expression in pancreatic ductal adenocarcinoma (PDAC), where its high levels are significantly correlated with metastatic progression. It elucidates that STAU2 directly binds and regulates PALLD, while mediating the functional role of IQGAP1, thereby driving metastasis ...
Jiayu Ding +16 more
wiley +1 more source
Not all roads lead to Cdk1 [PDF]
Cell Cycle, 2017 Branzei, Dana, Ciliberto, Andrea
openaire +3 more sources
Phosphorylation of AIB1 at Mitosis Is Regulated by CDK1/CYCLIN B
PLoS ONE, 2011 Although the AIB1 oncogene has an important role during the early phase of the cell cycle as a coactivator of E2F1, little is known about its function during mitosis.Mitotic cells isolated by nocodazole treatment as well as by shake-off revealed a post-translational modification occurring in AIB1 specifically during mitosis.
Ferrero, Macarena +6 more
openaire +9 more sources
Cell adhesion is regulated by CDK1 during the cell cycle
Journal of Cell Biology, 2018 In most tissues, anchorage-dependent growth and cell cycle progression are dependent on cells engaging extracellular matrices (ECMs) via integrin–receptor adhesion complexes.
Matthew C. Jones +3 more
semanticscholar +1 more source
Telomere length regulation: coupling DNA end processing to feedback regulation of telomerase [PDF]
, 2009 The conventional DNA polymerase machinery is unable to fully replicate the ends of linear chromosomes. To surmount this problem, nearly all eukaryotes use the telomerase enzyme, a specialized reverse transcriptase that utizes its own RNA template to add ...
Adams AK +15 more
core +3 more sources
Animal Research and One Health, EarlyView.Dietary supplement of sodium butyrate, may relate to regulating intestinal health and thus the growth performance and meat quality of rabbits by regulating the continuous process of promoting the periodic cycle of cecal epithelial cells. Abstract Supplementation of sodium butyrate (SB) has been proved to be beneficial for improving the growth ...
Mengke Ni +8 more
wiley +1 more source
Mastl/PP2A regulate Cdk1 in ooycte maturation
Oncotarget, 2015 Resumption of oocyte meiotic maturation is driven by activation of cyclin-dependent kinase 1 (Cdk1), which phosphorylates target proteins that are important for nuclear envelope breakdown, chromosome condensation, and remodelling of the actin and microtubule cytoskeleton.
Philipp Kaldis +3 more
openaire +3 more sources
Circ-ZNF609 regulates G1-S progression in rhabdomyosarcoma [PDF]
, 2019 Circular RNAs (circRNAs) represent a class of covalently closed RNAs, derived from non-canonical splicing events, which are expressed in all eukaryotes and often conserved among different species.
Bozzoni, Irene +9 more
core +1 more source