Results 201 to 210 of about 67,859 (329)

The Cyclin-Ubiquitin Ligase Activity of Cyclosome/APC Is Jointly Activated by Protein Kinases Cdk1-Cyclin B and Plk [PDF]

, 2002
Amnon Golan, Yana Yudkovsky, Avram Hershko   +2 more
openalex   +1 more source

Mining bioactive components in agricultural crop and food production residue for sustainable solutions: In silico screening for skin anti‐ageing properties

International Journal of Cosmetic Science, EarlyView.
A workflow for identifying sustainable anti‐ageing solutions from agricultural crop and food production residues (ACFPR). A combination of in silico techniques, like database interrogations, target predictions, molecular docking, and ADME predictions can pave the way for the development of innovative, eco‐friendly anti‐ageing cosmetics.
Senka Vidović, Milan Ilić, Jelena Nakomčić, Nataša Nastić, Jelena Kvrgić, Xuanpeng Song, Dimitar Jakimov, Aleksandra Jovanović Galović, Nataša Lješković Jovanović, Mire Zloh   +9 more
wiley   +1 more source

Yeast Cdk1 translocates to the plus end of cytoplasmic microtubules to regulate bud cortex interactions [PDF]

, 2003
Hiromi Maekawa
openalex   +1 more source

ESSENTIAL MEIOTIC ENDONUCLEASE 1 is required for chloroplast development and DNA repair in rice

Plant Biotechnology Journal, EarlyView.
Summary Chloroplast development is fundamental to photosynthesis and plant growth but is sensitive to environmental stress. Chloroplast development and division require genome stability and DNA repair, but the underlying mechanisms have been unclear. Using a forward genetic approach, we identified the striped‐leaf mutant k48 in the rice (Oryza sativa L.
Yanxin Du, Yang Li, Weijiang Tang, Weiping Mo, Tingting Ma, Rongcheng Lin   +5 more
wiley   +1 more source

Dual Targeting of Pim and PI3 Kinases in Mature T‐Cell Lymphoma

European Journal of Haematology, Volume 115, Issue 1, Page 82-95, July 2025.
ABSTRACT Provirus Integration site for Moloney leukemia virus (Pim) family members are well‐known oncogenes, with an expression that is restricted to few cell types including hematopoietic cells in adult organisms, making it a promising target for lymphoma treatment.
M. Lohrberg, M. Heber, L. Ries, K. Markus, N. Ksionsko, N. Schmidt, G. Nothnick, L. Thielking, M. O'Neill, S. Martínéz‐González, C. Blanco‐Aparicio, J. Pastor, D. Cunningham, R. Koch   +13 more
wiley   +1 more source

Meisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Meisoindigo targets PKMYT1 for degradation by acting as a molecular glue that enhances PKMYT1‐TRIM25 interaction, leading to K48‐linked ubiquitination and subsequent proteasomal degradation, thereby exerting therapeutic effects in chronic myeloid leukemia.
Zhao‐Xin Zhang, Shu‐Ying Li, Fang‐Fei Li, Qin‐Yan Shi, Cheng‐Yong Tan, Xiao‐Jing Wang, Mi Li, Yun‐Bao Liu, Jing Jin, Yong Li, Shi‐Shan Yu   +10 more
wiley   +1 more source

Cdc28/Cdk1 Regulates Spindle Pole Body Duplication through Phosphorylation of Spc42 and Mps1 [PDF]

, 2004
Sue L. Jaspersen, Brenda J. Huneycutt, Thomas H. Giddings, Katheryn A. Resing, Natalie G. Ahn, Mark Winey   +5 more
openalex   +1 more source

Unraveling the interplay between PKA inhibition and Cdk1 activation during oocyte meiotic maturation

Cell Reports
Summary: Oocytes are arrested in prophase I. In vertebrates, meiotic resumption is triggered by hormonal stimulation that results in cAMP-dependent protein kinase (PKA) downregulation leading to Cdk1 activation.
Martina Santoni, Ferdinand Meneau, Nabil Sekhsoukh, Sandrine Castella, Tran Le, Marika Miot, Enrico Maria Daldello   +6 more
doaj  

p21-Mediated Nuclear Retention of Cyclin B1-Cdk1 in Response to Genotoxic Stress [PDF]

, 2004
Fabienne Charrier‐Savournin, Marie‐Thérèse Château, Véronique Gire, John M. Sedivy, Jacques Piette, Vjekoslav Dulić   +5 more
openalex   +1 more source

Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition

Advanced Science, Volume 12, Issue 21, June 5, 2025.
This study shows that the classical secretory protein S100 calcium‐binding protein A9 (S100A9) can translocate to the nucleus upon de‐phosphorylation at Thr 113 in human amnion fibroblasts at parturition, where S100A9 induces heterochromatin erosion through segregation of the heterochromatin maintenance protein, resulting inLong Interspersed Nuclear ...
Fan Zhang, Meng‐Die Li, Fan Pan, Wen‐Jia Lei, Yang Xi, Li‐Jun Ling, Leslie Myatt, Kang Sun, Wang‐Sheng Wang   +8 more
wiley   +1 more source