Results 51 to 60 of about 46,551 (257)
Cells, 2023 The cyclin-dependent kinase 1 (Cdk1)–cyclin B (CycB) complex plays critical roles in cell-cycle regulation. Before Drosophila male meiosis, CycB is exported from the nucleus to the cytoplasm via the nuclear porin 62kD (Nup62) subcomplex of the nuclear ...
Kanta Yamazoe, Yoshihiro H. Inoue
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, 2020 This study aims to investigate the potential mechanisms and identify core biomarkers of Hepatocellular carcinoma (HCC). The profile GSE113850 was downloaded to analyze the differentially expressed genes.
Kang Huang (323555) +5 more
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Timing Is Everything: Regulation of Cdk1 and Aneuploidy [PDF]
Developmental Cell, 2007 The spindle checkpoint ensures the proper partition of the chromosomal content of dividing cells, by controlling the transition from metaphase to anaphase. In a recent issue of Cancer Cell, Vecchione and coworkers report that the protein product of the tumor suppressor gene Lzts1 (Leucine zipper tumor suppressor-1) binds the Cdk1 phosphatase Cdc25C and
Tsichlis, Philip N. +2 more
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Cdk1: Unsung Hero of S Phase? [PDF]
Cell Cycle, 2004 Cdk2 has been viewed as a key cell cycle regulator that is essential for S phase progression. The recent discovery that Cdk2 is not required for cell proliferation in mice now shows that other factors must be able to replace Cdk2 in stimulating DNA replication.
Marcin, Pacek +2 more
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Cancer Management and Research, 2020 Suying Lu,1,2,* Chengtao Sun,3,* Huimou Chen,1,2,* Chao Zhang,1,4,* Wei Li,5 Liuhong Wu,1,2 Jia Zhu,1,2 Feifei Sun,1,2 Junting Huang,1,2 Juan Wang,1,2 Zijun Zhen,1,2 Ruiqing Cai,1,2 Xiaofei Sun,1,2 Yizhuo Zhang,1,2 Xing Zhang1,6 1State Key Laboratory of ...
Lu S +14 more
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Drug Design, Development and Therapy, 2023 Mei Zhao,1,2 Lijuan Fu,1,2 Panling Xu,1,2 Ting Wang,1,2 Ping Li1,2 1Department of Chinese Integrative Medicine Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China; 2Department of Integrated Traditional ...
Zhao M, Fu L, Xu P, Wang T, Li P
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Dissection of Cdk1–cyclin complexes in vivo [PDF]
Proceedings of the National Academy of Sciences, 2013 Significance A simple strategy is described to discover cyclin dependency of general cell cycle regulatory kinase cyclin-dependent kinase 1 for substrates in vivo. γ-Tubulin is discovered to be a specific B cyclin Clb3–cyclin-dependent kinase 1 substrate.
Po Hien, Ear +7 more
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Cancer Management and Research, 2021 Deng YR, Chen XJ, Chen W, et al. Cancer Manag Res. 2019;11:5835–5844. The authors have advised due to an error at the time of figure assembly, Figure 3A on page 5840 is incorrect. The correct Figure 3 is shown in Download Article.
Deng YR +8 more
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Cancer Management and Research, 2020 Shufen Zhao,1 Baiyao Wang,2 Yanning Ma,3 Junjie Kuang,1 Jiyun Liang,3 Yawei Yuan1,2 1Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou City, Guangdong Province 510515, People’s Republic of China; 2Department
Zhao S +5 more
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Brain-derived neurotrophic factor-dependent cdk1 inhibition prevents G2/M progression in differentiating tetraploid neurons. [PDF]
PLoS ONE, 2013 Neurodegeneration is often associated with DNA synthesis in neurons, the latter usually remaining for a long time as tetraploid cells before dying by apoptosis.
María C Ovejero-Benito, José M Frade
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