Results 71 to 80 of about 67,859 (329)
Cdk1 and SUMO Regulate Swe1 Stability
PLoS ONE, 2010 The Swe1/Wee1 kinase phosphorylates and inhibits Cdk1-Clb2 and is a major mitotic switch. Swe1 levels are controlled by ubiquitin mediated degradation, which is regulated by interactions with various mitotic kinases. We have recently reported that Swe1 levels are capable of sensing the progress of the cell cycle by measuring the levels of Cdk1-Clb2 ...
Kobi J. Simpson-Lavy, Michael Brandeis
openaire +5 more sources
International Journal on Biological Sciences, 2021 The treatment of advanced prostate cancer, castration-resistant prostate cancer, remains challenging. The mechanisms of action of ATP binding cassette subfamily C member 5 (ABCC5) in prostate cancer and its relationship with drug resistance are still ...
G. Ji +5 more
semanticscholar +1 more source
High Expression of CDK1 and NDC80 Predicts Poor Prognosis of Bladder Cancer [PDF]
arXiv, 2021 Background: Bladder cancer is the 10th most common cancer worldwide, and its prevalence is increasing, especially in developing countries. Objective: In the present study, we employed gene expression profiles from the GSE163209 data set in the GEO database to identify potential molecular and genetic markers in BC patients.
arxiv
Microbiology spectrum, 2021 Japanese encephalitis virus (JEV) is the main cause of acute human encephalitis in Asia. The unavailability of specific treatment for Japanese encephalitis demands a better understanding of the basic cellular mechanisms that contribute to the onset of ...
Qiu-Yu Li +10 more
semanticscholar +1 more source
, 2019 The corn smut fungus uses two different mechanisms to control its cell cycle when it is infecting ...
Bardetti +8 more
core +1 more source
Drug Design, Development and Therapy, 2023 Mei Zhao,1,2 Lijuan Fu,1,2 Panling Xu,1,2 Ting Wang,1,2 Ping Li1,2 1Department of Chinese Integrative Medicine Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China; 2Department of Integrated Traditional ...
Zhao M, Fu L, Xu P, Wang T, Li P
doaj
Cdk1-dependent control of membrane-trafficking dynamics [PDF]
Molecular Biology of the Cell, 2012 Cyclin-dependent kinase 1 (Cdk1) is required for initiation and maintenance of polarized cell growth in budding yeast. Cdk1 activates Rho-family GTPases, which polarize the actin cytoskeleton for delivery of membrane to growth sites via the secretory pathway.
Christophe Velours +5 more
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Phosphorylation of eIF4GII and 4E-BP1 in response to nocodazole treatment: a reappraisal of translation initiation during mitosis [PDF]
, 2013 Translation mechanisms at different stages of the cell cycle have been studied for many years, resulting in the dogma that translation rates are slowed during mitosis, with cap-independent translation mechanisms favored to give expression of key ...
Abbie Mead +55 more
core +1 more source
CDK1 phosphorylates WRN at collapsed replication forks [PDF]
Nature Communications, 2016 AbstractRegulation of end-processing is critical for accurate repair and to switch between homologous recombination (HR) and non-homologous end joining (NHEJ). End resection is a two-stage process but very little is known about regulation of the long-range resection, especially in humans.
Valentina Palermo +8 more
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Cancer Management and Research, 2020 Shufen Zhao,1 Baiyao Wang,2 Yanning Ma,3 Junjie Kuang,1 Jiyun Liang,3 Yawei Yuan1,2 1Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou City, Guangdong Province 510515, People’s Republic of China; 2Department
Zhao S +5 more
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