Results 71 to 80 of about 266,442 (278)

5th Central-Eastern European Congress on Cell-Free Nucleic Acids

Biomedical Papers, 2018
21st-22nd June, 2018.
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doaj  

Cell-Free Nucleic Acids as Biomarkers of Biocompatibility in Dialytic Process [PDF]

, 2011
In this review we describe what is recently known about the origin of free nucleic acids in human circulation, which processes can cause the elevations of their total concentrations and the alterations in the ratios among different types of circulating nucleic acids in human plasma and serum.
Marie Korabecna, Ales Horinek
openaire   +1 more source

Cell division promotes efficient retrotransposition in a stable L1 reporter cell line [PDF]

, 2013
Background: Long interspersed element type one (L1) actively modifies the human genome by inserting new copies of itself. This process, termed retrotransposition, requires the formation of an L1 ribonucleoprotein (RNP) complex, which must enter the ...
Ivics, Z., Zsuzsanna Izsvák, Lajos Mates, Ivics, Zoltán, Izsvák, Zsuzsanna, Martin, Sandra L., Xie, Y., An, Wenfeng, Mátés, Lajos, Xie, Yi, Yi Xie, Sandra L Martin, An, W., Mates, L., Martin, S.L., Izsvák, Z., Wenfeng An, Zoltán Ivics   +17 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity

, 2013
hSSB1 is a recently discovered single-stranded DNA binding protein that is essential for efficient repair of DNA double-strand breaks (DSBs) by the homologous recombination pathway.
Bain, Amanda, Khanna, Kum Kum, Menon, Dinoop, White, Malcolm F., Richard, Derek J., Urquhart, Aaron J., Bolderson, Emma, Cubeddu, Liza   +7 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Quantitative studies of nucleic acids in the cell with microspectrophotometer. II. Nucleic acid and hemoglobin contents in erythroid cells of frog and hen

, 1959
Using the erythroid cells of Rana nigromaculata the hemoglobin synthesis has been studied in the relation of DNA and RNA contents. Results showed that the hemoglobin synthesis starts in the early stage of erythroblast but becomes marked just before the ...
Utsumi, Kozo
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Survival outcomes correlate with the level of cell-free circulating DNA in ST-elevation myocardial infarction

Journal of Research in Medical Sciences
Background: Myocardial infarction (MI) can lead to higher cellular damage, making cell-free DNA (cfDNA) a potential biomarker for assessing disease severity.
Ai-Ai Chu, Han-Xiang Gao, Ting-Ting Wu, Zheng Zhang   +3 more
doaj   +1 more source