Results 21 to 30 of about 6,549,693 (278)
Advances in Cancer Biology - Metastasis, 2021 Cancer treatment is an economic burden because of the very expensive drugs which depend on improvement in modern technology. Furthermore, the rate of success of cancer treatments is not actually satisfying.
Aritra Kumar Dan +6 more
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Regrowth resistance: low-level platinum resistance mediated by rapid recovery from platinum-induced cell-cycle arrest [PDF]
, 2009 The H69CIS200 and H69OX400 cell lines are novel models of low-level platinum drug resistance developed from H69 human small cell lung cancer cells with eight 4-day treatments of 200 ng/ml cisplatin or 400 ng/ml oxaliplatin respectively. A recovery period
Ross Davey +3 more
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PLoS Biology, 2010 DNA damage checkpoints arrest cell cycle progression to facilitate DNA repair. The ability to survive genotoxic insults depends not only on the initiation of cell cycle checkpoints but also on checkpoint maintenance.
Marcel A T M van Vugt +15 more
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Molecular mechanisms creating bistable switches at cell cycle transitions [PDF]
Open Biology, 2013 Progression through the eukaryotic cell cycle is characterized by specific transitions, where cells move irreversibly from stage i−1 of the cycle into stage i. These irreversible cell cycle transitions are regulated by underlying bistable switches, which
Anael Verdugo +3 more
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Ca2+ signals co-ordinate zygotic polarization and cell cycle progression in the brown alga, Fucus serratus. [PDF]
, 2008 Zygotes of the fucoid brown algae provide excellent models for addressing fundamental questions about zygotic symmetry breaking. Although the acquisition of polarity is tightly coordinated with the timing and orientation of the first asymmetric division ...
Bothwell, John H. F. +4 more
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Human checkpoint proteins hRad9, hHus1, and hRad1 form a DNA damage-responsive complex [PDF]
, 2004 Human cells have evolved protective mechanisms such as DNA repair and cell cycle checkpoints in order to promote stability of the genome. Studies on hereditary instability syndromes associated with a higher incidence of malignancies like Xeroderma ...
Volkmer, Elias
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Evolutionary Divergence in DNA Damage Responses among Fungi
mBio, 2021 Cell cycle checkpoints and DNA repair pathways contribute to maintaining genome integrity and are thought to be evolutionarily ancient and broadly conserved.
Jacob L. Steenwyk
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Cell cycle, checkpoints and cancer [PDF]
, 2014 Deep insight on Cell cycle, checkpoints and ...
Carrassa, L
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Modulations of cell cycle checkpoints during HCV associated disease
BMC Infectious Diseases, 2009 Background Impaired proliferation of hepatocytes has been reported in chronic Hepatitis C virus infection. Considering the fundamental role played by cell cycle proteins in controlling cell proliferation, altered regulation of these proteins could ...
Jafri Wasim +4 more
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Probing Mammalian Cell Size Homeostasis by Channel-Assisted Cell Reshaping
Cell Reports, 2017 Cell size homeostasis can be achieved by size checkpoints that couple cell size to cell-cycle progression or by alternative mechanisms such as constant extension.
Giulia Varsano, Yuedi Wang, Min Wu
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