Results 221 to 230 of about 400,889 (317)

Genetic map of the carotid body stem cell niche with focus on the O₂-sensing chemoreceptor cell lineage. [PDF]

Sci Rep
Santamaría-Santiago A, Sobrino V, Luna-Ramírez L, López-Barneo J, Pardal R.   +4 more
europepmc   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Key Common Genes with LTF and MMP9 Between Sepsis and Relapsed B-Cell Lineage Acute Lymphoblastic Leukemia in Children. [PDF]

Biomedicines
Xiao YP, Cheng YC, Chen C, Xue HM, Yang M, Lin C.   +5 more
europepmc   +1 more source

The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage

, 2015
Linsey E. Lindley, Kevin M. Curtis, Avencia Sánchez-Mejías, Megan E. Rieger, David J. Robbins, Karoline J. Briegel   +5 more
openalex   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

Advancements in prospective single-cell lineage barcoding and their applications in research. [PDF]

Genome Res
Zhang X, Huang Y, Yang Y, Wang QE, Li L.
europepmc   +1 more source

Lineage-specific silencing of human IL-10 gene expression by promoter methylation in cervical cancer cells

, 2008
Anita Szalmás, Ferenc Bánáti, Anita Koroknai, Brigitta László, Enikő Fehér, Dániel Salamon, Lajos Gergely, János Minárovits, József Kónya   +8 more
openalex   +2 more sources

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Promising Drugs Targeting Specific Mechanisms of Deregulation in T Cell Lineage Acute Lymphoblastic Leukemia. [PDF]

Oncol Ther
Thomas X.
europepmc   +1 more source

Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages

, 2015
MacLean Sellars, Jun R. Huh, Kenneth Day, Priya D. Issuree, Carolina Galan, Stéphane Gobeil, Devin Absher, Michael R. Green, Dan R. Littman   +8 more
openalex   +1 more source