Results 1 to 10 of about 12,335,534 (353)
Supracellular migration – beyond collective cell migration [PDF]
Journal of Cell Science, 2019 ABSTRACT Collective cell migration is a highly complex process in which groups of cells move together. A fundamental question is how cell ensembles can migrate efficiently. In some cases, the group is no more than a collection of individual cells.
Adam Shellard, Roberto Mayor
openaire +4 more sources
The Tyrosine Kinase Pyk2 Promotes Migration and Invasion of Glioma Cells
Neoplasia: An International Journal for Oncology Research, 2005 Glioblastoma multiforme is extraordinarily aggressive due to the propensity of cells to migrate away from the tumor core into the surrounding normal brain.
Christopher A. Lipinski +7 more
doaj +2 more sources
Invadopodia, a Kingdom of Non-Receptor Tyrosine Kinases
Cells, 2021 Non-receptor tyrosine kinases (NRTKs) are crucial mediators of intracellular signaling and control a wide variety of processes such as cell division, morphogenesis, and motility.
Trishna Saha, Hava Gil-Henn
doaj +1 more source
Intermediate Filaments from Tissue Integrity to Single Molecule Mechanics
Cells, 2021 Cytoplasmic intermediate filaments (IFs), which together with actin and microtubules form the cytoskeleton, are composed of a large and diverse family of proteins.
Emma J. van Bodegraven +1 more
doaj +1 more source
Dendritic cell migration in inflammation and immunity
Cellular & Molecular Immunology, 2021 Dendritic cells (DCs) are the key link between innate immunity and adaptive immunity and play crucial roles in both the promotion of immune defense and the maintenance of immune tolerance.
Juan Liu +3 more
semanticscholar +1 more source
Are We Ready for Migrastatics?
Cells, 2021 Metastasis accounts for the highest mortality rates in solid tumor cancer patients. However, research and development have neglected this most lethal characteristic and, instead, have concentrated on the hallmarks of cancer that make tumor cells highly ...
Jonathan Solomon +4 more
doaj +1 more source
PTEN inhibits AMPK to control collective migration
Nature Communications, 2022 Pten is a tumour suppressor gene that is associated with highly invasive cancers such as glioblastoma. Here the authors show that PTEN loss results in increased migratory behaviour, which can be countered by targeting AMPK activity.
Florent Peglion +9 more
doaj +1 more source
Unravelling cell migration: defining movement from the cell surface
Cell Adhesion & Migration, 2022 Cell motility is essential for life and development. Unfortunately, cell migration is also linked to several pathological processes, such as cancer metastasis. Cells’ ability to migrate relies on many actors.
Francisco Merino-Casallo +3 more
semanticscholar +1 more source
Pannexin Channel Regulation of Cell Migration: Focus on Immune Cells
Frontiers in Immunology, 2021 The role of Pannexin (PANX) channels during collective and single cell migration is increasingly recognized. Amongst many functions that are relevant to cell migration, here we focus on the role of PANX-mediated adenine nucleotide release and associated ...
Paloma A. Harcha +3 more
doaj +1 more source
U1 snRNP regulates cancer cell migration and invasion in vitro
Nature Communications, 2020 Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter mRNA isoforms due to usage of more proximal polyadenylation signals (PASs) in introns and last exons. U1 snRNP (U1), vertebrates’
Jung-Min Oh +10 more
semanticscholar +1 more source