Results 1 to 10 of about 114,739 (248)
Context-Dependent Impact of RAS Oncogene Expression on Cellular Reprogramming to Pluripotency [PDF]
Stem Cell Reports, 2019 Summary: Induction of pluripotency in somatic cells with defined genetic factors has been successfully used to investigate the mechanisms of disease initiation and progression.
Alba Ferreirós +12 more
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Deepening the understanding of CNVs on chromosome 15q11–13 by using hiPSCs: An overview
Frontiers in Cell and Developmental Biology, 2023 The human α7 neuronal nicotinic acetylcholine receptor gene (CHRNA7) is widely expressed in the central and peripheral nervous systems. This receptor is implicated in both brain development and adult neurogenesis thanks to its ability to mediate ...
Angela Maria Giada Giovenale +11 more
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Cellular internalization effect of Ara27 in various cell lines
Journal of Animal Reproduction and Biotechnology, 2022 Protein and peptide candidates are screened to apply therapeutic application as a drug. Ensuring that these candidates are delivered and maximized effectiveness is still challenging and a variety of studies are ongoing.
Minseo Kim +3 more
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Human Neural Stem Cells for Cell-Based Medicinal Products
Cells, 2021 Neural stem cells represent an attractive tool for the development of regenerative therapies and are being tested in clinical trials for several neurological disorders.
Beatriz Fernandez-Muñoz +3 more
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Stem Cell Research & Therapy, 2022 Background Bone has important functions in the body. Several researchers have reported that the polysaccharides and lipopolysaccharide derived from microbes can promote osteogenic differentiation of stem cells.
Hyewon Kim +6 more
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Antioxidants, 2021 Extracellular vesicles (EVs) are paracrine factors that mediate stem cell therapeutics. We aimed at evaluating the possible therapeutic and esthetic applications of EVs prepared from the waste human facial tissue-derived orbicularis oculi muscle stem ...
Kyung Min Lim +10 more
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Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals
Genome Biology, 2021 Background Precise gene dosage of the X chromosomes is critical for normal development and cellular function. In mice, XX female somatic cells show transcriptional X chromosome upregulation of their single active X chromosome, while the other X ...
Irene Talon +13 more
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Molecules, 2021 Salivary gland stem cells (SGSCs) are potential cell sources for the treatment of salivary gland diseases. The control of cell survival is an essential factor for applying stem cells to regenerative medicine or stem cell-based research.
Kichul Kim +4 more
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Molecules, 2020 Human malignant melanoma is the most aggressive type of skin cancer with high metastatic ability. Despite several traditional therapies, the mortality rate remains high. Lactobacillus plantarum (L.
Jaehyun Park +5 more
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Journal of Translational Medicine, 2023 Background The incidence of bladder cancer (BCa) is approximately four times higher in men than in women. To develop effective BCa treatments, there is an urgent need to understand the differences in the BCa control mechanisms based on gender. Our recent
Jaekwon Seok +6 more
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