Results 11 to 20 of about 114,739 (248)

Pluripotent Stem Cells for Spinal Cord Injury Repair

Cells, 2021
Spinal cord injury (SCI) is a devastating condition of the central nervous system that strongly reduces the patient’s quality of life and has large financial costs for the healthcare system.
Maria Martin-Lopez, Beatriz Fernandez-Muñoz, Sebastian Canovas   +2 more
doaj   +1 more source

Isolation of female germline stem cells from porcine ovarian tissue and differentiation into oocyte-like cells

The Journal of Reproduction and Development, 2019
Historically, it had been widely accepted that the female mammalian ovary contained a limited number of oocytes that would reduce over time, without the possibility of replenishment. However, recent studies have suggested that female germline stem cells (
Huy-Hoang NGUYEN, Bui Le Quynh NHU, Nguyen Nhat Phuong UYEN, Van-Thuan NGUYEN, Hong-Thuy BUI   +4 more
doaj   +1 more source

Thermostable Human Basic Fibroblast Growth Factor (TS-bFGF) Engineered with a Disulfide Bond Demonstrates Superior Culture Outcomes in Human Pluripotent Stem Cell

Biology, 2023
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) can differentiate into various tissues and are an essential source of various disease models and therapeutics.
Sejong Kim, Geun-Ho Kang, Kyung Min Lim, Yeokyung Shin, Kwonwoo Song, Sangrok Park, Jongyub An, Dae Young Kim, Hang-Cheol Shin, Ssang-Goo Cho   +9 more
doaj   +1 more source

Epigenetic impairments in development of parthenogenetic preimplantation mouse embryos

The Journal of Reproduction and Development, 2018
Parthenogenesis is an activation process of oocytes that occur without the participation of sperm. Evidence suggests that normal development of embryos requires proper expression of several imprinted genes inherited from both the paternal and maternal ...
Ngan Thi Kim HO, Thuy Van Thi NGUYEN, Thuan Van NGUYEN, Hong-Thuy BUI   +3 more
doaj   +1 more source

Autophagy: A Key Regulator of Homeostasis and Disease: An Overview of Molecular Mechanisms and Modulators

Cells, 2022
Autophagy is a highly conserved lysosomal degradation pathway active at basal levels in all cells. However, under stress conditions, such as a lack of nutrients or trophic factors, it works as a survival mechanism that allows the generation of metabolic ...
Laura Gómez-Virgilio, Maria-del-Carmen Silva-Lucero, Diego-Salvador Flores-Morelos, Jazmin Gallardo-Nieto, Gustavo Lopez-Toledo, Arminda-Mercedes Abarca-Fernandez, Ana-Elvira Zacapala-Gómez, José Luna-Muñoz, Francisco Montiel-Sosa, Luis O. Soto-Rojas, Mar Pacheco-Herrero, Maria-del-Carmen Cardenas-Aguayo   +11 more
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Cyclopamine, an Antagonist of Hedgehog (Hh) Signaling Pathway, Reduces the Hatching Rate of Parthenogenetic Murine Embryos

Journal of Animal Reproduction and Biotechnology, 2018
Hedgehog (Hh) pathway plays a key role in development from invertebrate to vertebrate. It is known to be involved in cell differentiation, polarity, proliferation, including the development of vertebrate limb and the establishment of flies’ body plan. To
Jaehyun Park, Jeonghyeon Moon, So Min, Stephan Chae, Sangho Roh   +4 more
doaj   +1 more source

Molecular versatility during pluripotency progression

Nature Communications, 2023
During development the embryo must balance lineage specification against the preservation of plasticity using a limited molecular toolkit. In this Perspective, the authors propose Molecular Versatility as a paradigm for grouping molecular mechanisms that
Giacomo Furlan, Aurélia Huyghe, Noémie Combémorel, Fabrice Lavial   +3 more
doaj   +1 more source

Enzymatic isolation of porcine preantral follicles impairs oocyte viability and long-term in vitro growth

The Journal of Reproduction and Development
The enzymatic isolation of preantral follicles (PAFs) is considered the most efficient method for retrieving a large number of intact follicles, offering significant advantages in terms of yield and processing time.
Ba Anh My LE, Lien Boi Linh NGUYEN, Phuong Thanh NGUYEN, Ha Nhat Lam VO, Ngoc Song Thu TRAN, Bao Nghi TRAN, Ngoc Thao Vy NGUYEN, Chi Thien LAM, Nhat-Thinh NGUYEN, Van Thuan NGUYEN, Hong-Thuy BUI   +10 more
doaj   +1 more source

Inhibition of Polo-like Kinase 1 Prevents the Male Pronuclear Formation Via Alpha-tubulin Recruiting in In Vivo-fertilized Murine Embryos

Journal of Animal Reproduction and Biotechnology, 2018
Polo-like kinase 1 (Plk1) has been known to be a critical element in cell division including centrosome maturation, cytokinesis and spindle formation in somatic, cancer, and mammalian embryonic cells.
Jeonghyeon Moon, Sangho Roh
doaj   +1 more source

Improving porcine in vitro blastocyst development using fetal bovine serum, amino acids, and insulin-transferrin-selenium

The Journal of Reproduction and Development
In vitro production of porcine-hatched blastocysts is important for various applications. However, the mechanobiology of blastocoel expansion and hatching remains poorly understood.
Ba Anh My LE, Lien Boi Linh NGUYEN, Chi Thien LAM, Nhat-Thinh NGUYEN, Ngoc Thao Vy NGUYEN, Van Thuan NGUYEN, Hong-Thuy BUI   +6 more
doaj   +1 more source