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Eight Up-Coming Biotech Tools to Combat Climate Crisis
Microorganisms, 2023 Biotechnology has a high potential to substantially contribute to a low-carbon society. Several green processes are already well established, utilizing the unique capacity of living cells or their instruments.
Werner Fuchs +5 more
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International Journal of Biological MacromoleculesThe development of cellulases cocktails to efficiently solubilize cellulose for biotechnological applications is a constant demand. Cellulases exhibit diverse mode of action, operating in the free state or in multi-enzyme complexes (cellulosomes), and potentially acting synergistically for a higher efficiency.
David, Hélène +6 more
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Green CarbonThe bioconversion of lignocellulose has attracted global attention, due to the significant potential of agricultural and forestry wastes as renewable zero-carbon resources and the urgent need for substituting fossil carbon.
Min Xiao +5 more
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Impact of scaffoldin mechanostability on cellulosomal activity
Biomaterials Science, 2020 A low mechanostability cohesin between the two cellulosomal anchoring points lowers saccharification activity (top), in contrast to alternative configurations (bottom).
Albert Galera-Prat +5 more
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Cellulosomics of the cellulolytic thermophile Clostridium clariflavum [PDF]
Biotechnology for Biofuels, 2014 Clostridium clariflavum is an anaerobic, thermophilic, Gram-positive bacterium, capable of growth on crystalline cellulose as a single carbon source. The genome of C. clariflavum has been sequenced to completion, and numerous cellulosomal genes were identified, including putative scaffoldin and enzyme subunits.Bioinformatic analysis of the C ...
Artzi, Lior +5 more
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Microbial Cell Factories, 2011 Background The recalcitrant nature of cellulosic materials and the high cost of enzymes required for efficient hydrolysis are the major impeding steps to their practical usage for ethanol production.
Madan Bhawna +4 more
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Toward Efficient Cellulosic Biomass Breakdown: Enzymatic Innovation and Kinetic Insights
Macromolecular Materials and Engineering, Volume 311, Issue 6, June 2026.By combining a processive GH7, CBM2a, and GH3 into single enzyme, the GCG fusion protein effectively breaks down crystalline cellulose. This tri‐domain architecture reduces cellobiose inhibition at the cellulose surface allowing for the simultaneous targeting of the substrate, depolymerization, and removal of products.
Anoth Maharjan +4 more
wiley +1 more source
The Cellulosome Paradigm in An Extreme Alkaline Environment
Microorganisms, 2019 Rapid decomposition of plant biomass in soda lakes is associated with microbial activity of anaerobic cellulose-degrading communities. The alkaliphilic bacterium, Clostridium alkalicellulosi, is the single known isolate from a soda lake that demonstrates cellulolytic activity.
Paripok Phitsuwan +4 more
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Organization and distribution of the cellulosome in Clostridium thermocellum [PDF]
Journal of Bacteriology, 1985 The properties of the cellulosome (the cellulose-binding, multicellulase-containing protein complex) in Clostridium thermocellum were examined by comparing the cellulase systems derived from the wild type and an adherence-defective mutant. The growth conditions--specifically, growth either on cellulose (Avicel) or on cellobiose as insoluble or soluble ...
E A, Bayer, E, Setter, R, Lamed
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Harnessing microbial power to degrade hydrocarbon‐based plastics
mLife, Volume 5, Issue 3, Page 263-281, June 2026.Abstract The growing global plastic waste crisis demands the development of urgent, effective, and sustainable solutions. While conventional recycling methods present intrinsic limitations, microbial biodegradation of plastic waste has emerged as a promising alternative.
Hui Li +4 more
wiley +1 more source