Results 11 to 20 of about 600,930 (299)

Antibody-mediated central nervous system diseases [PDF]

Brain and Neuroscience Advances, 2018
Antibody-mediated central nervous system diseases are a relatively new area of clinical neuroscience with growing impact. Their recognition has challenged the dogma of the blood–brain barrier preventing antibody access into the central nervous system ...
Maria Pia Giannoccaro, Sarah J. Crisp, Angela Vincent   +2 more
doaj   +4 more sources

Central nervous system manifestations in rheumatic diseases [PDF]

Journal of Medical Biochemistry, 2011
Neurological involvement is associated with significant morbidity in patients with rheumatic diseases, and may indicate heightened disease activity. Connective tissue diseases result from immunologic or autoimmune reactions.
Cojocaru Mihaela Inimioara, Cojocaru Manole, Silosi Isabela, Vrabie Doina Camelia   +3 more
doaj   +2 more sources

Microglia lactylation in relation to central nervous system diseases [PDF]

Neural Regeneration Research
The development of neurodegenerative diseases is closely related to the disruption of central nervous system homeostasis. Microglia, as innate immune cells, play important roles in the maintenance of central nervous system homeostasis, injury response ...
Hui Yang, Nan Mo, Le Tong, Jianhong Dong, Ziwei Fan, Mengxian Jia, Juanqing Yue, Ying Wang   +7 more
doaj   +2 more sources

The microbiota-gut-brain axis and central nervous system diseases: from mechanisms of pathogenesis to therapeutic strategies. [PDF]

Front Microbiol
Xu J, Lu Y.
europepmc   +3 more sources

Central nervous system Whipple's disease [PDF]

Annals of Neurology, 1997
Contains fulltext : 25412___.PDF (Publisher’s version ) (Open Access)
Verhagen, W.I.M., Huygen, P.L.M., Dalman, J.E.   +2 more
openaire   +4 more sources

Brainstem syndrome at onset is related to an early MS diagnosis in Peru: A national referral center cohort

Heliyon, 2021
Background: MS is unpredictable regarding clinical symptoms; however, certain symptoms represent the preferred localization of white matter lesions such as brainstem, spinal cord; or optic nerve.
César Caparó-Zamalloa, Sheila Castro-Suarez, Jaqueline Cortez-Escalante, Wilfor Aguirre-Quispe, Erik Guevara-Silva, Victor Osorio-Marcatinco, María Meza-Vega   +6 more
doaj   +1 more source

Effects of the mGlu2/3 receptor agonist LY379268 on two models of disturbed auditory evoked brain oscillations in mice

Translational Psychiatry, 2023
Cognitive impairment is a core feature of schizophrenia and is poorly addressed by currently available medication. This is partly because the underlying circuits are insufficiently understood, and available animal models for brain dysfunction do not ...
Oana-Daniela Dormann, Niklas Schuelert, Holger Rosenbrock   +2 more
doaj   +1 more source

RETRACTED ARTICLE: GRP78 determines glioblastoma sensitivity to UBA1 inhibition-induced UPR signaling and cell death

Cell Death and Disease, 2021
Glioblastoma multiforme (GBM) is an extremely aggressive brain tumor for which new therapeutic approaches are urgently required. Unfolded protein response (UPR) plays an important role in the progression of GBM and is a promising target for developing ...
Guanzheng Liu, Jiefeng Yu, Runqiu Wu, Lin Shi, Xu Zhang, Wanhong Zhang, Xiaomin Zhong, Yifeng Wang, Huan Li, Yang Shen, Changyong Wu, Rutong Yu, Mingshan Niu, Xuejiao Liu   +13 more
doaj   +1 more source

Effects of Tocilizumab Therapy on Circulating B Cells and T Helper Cells in Patients With Neuromyelitis Optica Spectrum Disorder

Frontiers in Immunology, 2021
Tocilizumab, a humanized anti-IL-6 receptor monoclonal antibody, showed its therapeutic efficacy on neuromyelitis optica spectrum disorder (NMOSD).
Ye Liu, Huiming Zhang, Tian-Xiang Zhang, Meng Yuan, Chen Du, Pei Zeng, Zhenning Huang, Dongmei Jia, Guili Yang, Fu-Dong Shi, Fu-Dong Shi, Chao Zhang, Chao Zhang   +12 more
doaj   +1 more source

Exploration of cerebral vasospasm from the perspective of microparticles

Frontiers in Neuroscience, 2022
Cerebral vasospasm is a frequently encountered clinical problem, especially in patients with traumatic brain injury and subarachnoid hemorrhage. Continued cerebral vasospasm can cause cerebral ischemia, even infarction and delayed ischemic neurologic ...
Yalong Gao, Kai Li, Xiaotian Li, Qifeng Li, Jiwei Wang, Jiwei Wang, Shu Zhang, Jianning Zhang   +7 more
doaj   +1 more source