Results 91 to 100 of about 27,287 (301)

Revisiting the Role of the Mother Centriole in Centriole Biogenesis [PDF]

Science, 2007
Centrioles duplicate once in each cell division cycle through so-called templated or canonical duplication. SAK, also called PLK4 (SAK/PLK4), a kinase implicated in tumor development, is an upstream regulator of canonical biogenesis necessary for centriole formation.
Rodrigues Martins, A., Riparbelli, M. G., Callaini, G., Glover, D. M., Bettencourt, D.   +4 more
openaire   +4 more sources

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Dynamics of centriole amplification in centrosome-depleted brain multiciliated progenitors

Scientific Reports, 2019
Reproductive and respiratory organs, along with brain ventricles, are lined by multiciliated epithelial cells (MCC) that generate cilia-powered fluid flows.
Olivier Mercey, Adel Al Jord, Philippe Rostaing, Alexia Mahuzier, Aurélien Fortoul, Amélie-Rose Boudjema, Marion Faucourt, Nathalie Spassky, Alice Meunier   +8 more
doaj   +1 more source

Common themes in centriole and centrosome movements. [PDF]

, 2013
addresses: School of Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford, OX3 0BP, UK.Copyright © 2011 Elsevier. NOTICE: this is the author’s version of a work that was accepted for publication in Trends in Cell Biology.
Allen, Basto, Beisson, Boisvieux-Ulrich, Boisvieux-Ulrich, Boisvieux-Ulrich, Bornens, Brugerolle, Burakov, Carreno, Chevrier, Cowan, Cowan, Dammermann, Dawe, Dawe, Dawe, Desai, Dupin, Etienne-Manneville, Etienne-Manneville, Euteneuer, Fan, Feldman, Finetti, Goldstein, Gomes, Gonczy, Gray, Griffiths, Griffiths, Gull, Helen R. Dawe, Higginbotham, Hirota, Hong, Jenkins, Jolly, Jolly, Karsenti, Kemphues, Kim, Klotz, Koonce, Kuhn, Kunda, Kunda, Lemullois, Lemullois, Lin, Ludford-Menting, Magdalena, Mahoney, Malone, Manneville, Moreira-Leite, Nejmeddine, Nigg, Palazzo, Pan, Park, Park, Pegtel, Piel, Piguet, Prigozhina, Raff, Riento, Rios, Robinson, Robinson, Rosenblatt, Roux, Ryser, Salpingidou, Schmoranzer, Scholey, Siegrist, Sonneville, Starr, Stinchcombe, Stinchcombe, Stowers, Sue Vaughan, Tabuse, Tanaka, Thery, Toyoshima, Tsai, Tsai, Tsou, Valente, Vaughan, Walczak, Wiedemann, Woolner, Worman, Wright, Yamashita, Zhang, Zhang, Zhen   +101 more
core   +1 more source

Titin Is Present in the Elastic Tethers That Connect Separating Anaphase Chromosomes in Crane‐Fly Spermatocytes

Cytoskeleton, EarlyView.
ABSTRACT Elastic tethers connect telomeres of separating chromosomes in anaphase of animal cells. Immunofluorescence staining of titin in crane‐fly spermatocytes, using 4 different antibodies, shows that the giant elastic protein titin seems to be a component of mitotic tethers: titin “strands” extend between separating chromosomes, connecting their ...
Demetra Economopoulos, Maral Janan, Martina Krüger, Aavo‐Valdur Mikelsaar, Arthur Forer, Rose Sheykhani   +5 more
wiley   +1 more source

With Age Comes Maturity: Biochemical and Structural Transformation of a Human Centriole in the Making

Cells, 2020
Centrioles are microtubule-based cellular structures present in most human cells that build centrosomes and cilia. Proliferating cells have only two centrosomes and this number is stringently maintained through the temporally and spatially controlled ...
Catherine Sullenberger, A. Vásquez-Limeta, Dong Kong, J. Loncarek   +3 more
semanticscholar   +1 more source

Identification of novel genes regulating the development of the palate

Developmental Dynamics, EarlyView.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

The Role of Sperm Centrioles in Human Reproduction – The Known and the Unknown

Frontiers in Cell and Developmental Biology, 2019
Each human spermatozoon contains two remodeled centrioles that it contributes to the zygote. There, the centrioles reconstitute a centrosome that assembles the sperm aster and participate in pronuclei migration and cleavage. Thus, centriole abnormalities
Tomer Avidor-Reiss, Tomer Avidor-Reiss, Matthew Mazur, Matthew Mazur, Emily L. Fishman, Puneet Sindhwani, Puneet Sindhwani   +6 more
doaj   +1 more source

Requirement of the Cep57-Cep63 Interaction for Proper Cep152 Recruitment and Centriole Duplication

Molecular and Cellular Biology, 2020
Cep57 has been characterized as a component of a pericentriolar complex containing Cep63 and Cep152. Interestingly, Cep63 and Cep152 self-assemble into a pericentriolar cylindrical architecture, and this event is critical for the orderly recruitment of ...
Zhuang Wei, Tae-Sung Kim, J. I. Ahn, Lingjun Meng, Yaozong Chen, E. Ryu, B. Ku, Ming Zhou, Seung Jun Kim, J. Bang, J. V. van Deursen, Jung-Eun Park, Kyung S. Lee   +12 more
semanticscholar   +1 more source

SnapShot: Centriole Biogenesis

Cell, 2009
SPD2 (Ce, Dm)/CEP192 (Hs)No centriole duplication (Ce);
Bettencourt-Dias, Mónica, Glover, David M.   +1 more
openaire   +3 more sources