Results 81 to 90 of about 13,342 (208)

Centrioles in symmetric spaces [PDF]

Nagoya Mathematical Journal, 2013
AbstractWe describe all centrioles in irreducible simply connected pointed symmetric spaces of compact type in terms of the root system of the ambient space, and we study some geometric properties of centrioles.
openaire   +4 more sources

Centrioles: Bad to Be Bald? [PDF]

Current Biology, 2004
In the alga Chlamydomonas, mutation of the gene encoding the novel centriolar component Bld10p results in seemingly acentriolar cells. Remarkably, bld10 cells are viable, highlighting the question of whether or not centrioles are essential.
Feldman, Jessica L., Marshall, Wallace F.   +1 more
openaire   +2 more sources

Mouse SAS-6 is required for centriole formation in embryos and integrity in embryonic stem cells

eLife
SAS-6 (SASS6) is essential for centriole formation in human cells and other organisms but its functions in the mouse are unclear. Here, we report that Sass6-mutant mouse embryos lack centrioles, activate the mitotic surveillance cell death pathway, and ...
Marta Grzonka, Hisham Bazzi
doaj   +1 more source

Patterns of selection against centrosome amplification in human cell lines.

PLoS Computational Biology, 2021
The presence of extra centrioles, termed centrosome amplification, is a hallmark of cancer. The distribution of centriole numbers within a cancer cell population appears to be at an equilibrium maintained by centriole overproduction and selection ...
Marco António Dias Louro, Mónica Bettencourt-Dias, Claudia Bank   +2 more
doaj   +1 more source

Archaeal Cytoskeletal Protein CetZ1 Influences Assembly of the Motility Machinery

Molecular Microbiology, EarlyView.
The Haloferax volcanii tubulin‐like protein CetZ1 is required for rod‐cell morphogenesis and motility. We show that CetZ1 loss or GTPase inactivation impairs assembly of the motility machinery, including the archaellum base protein ArlD, the chemotaxis adaptor CheW1, and the response regulator CheY.
Hannah J. Brown, Md Imtiazul Islam, Juanfang Ruan, Matthew A. B. Baker, Solenne Ithurbide, Iain G. Duggin   +5 more
wiley   +1 more source

CRISPR/Cas9‐mediated Genome‐editing Reveals 10 Testis‐enriched Genes and One Non‐testis‐enriched Gene are Dispensable for Male Fecundity in Mice

Andrology, Volume 14, Issue 7, Page 2150-2159, October 2026.
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu, Keisuke Shimada, Masahito Ikawa   +2 more
wiley   +1 more source

Centrioles go for a stroll [PDF]

Nature, 2000
In most animal cells, a pair of centrioles resides in the centrosome —an organelle that organizes the cell's microtubule system. It has long been thought that the two centrioles always remain at right angles to each other. It seems, however, that the 'daughter' centriole roams extensively throughout the cell.
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Centriole assembly at a glance [PDF]

Journal of Cell Science, 2019
ABSTRACT The centriole organelle consists of microtubules (MTs) that exhibit a striking 9-fold radial symmetry. Centrioles play fundamental roles across eukaryotes, notably in cell signaling, motility and division. In this Cell Science at a Glance article and accompanying poster, we cover the cellular life cycle of this organelle – from ...
Gönczy, Pierre, Hatzopoulos, Georgios
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A novel atypical sperm centriole is functional during human fertilization

Nature Communications, 2018
The two zygote centrioles are paternally inherited; however, their development is incompletely understood. Here, the authors show that the distal centriole is remodeled into an atypical centriole which functions as the zygote’s second centriole.
Emily L. Fishman, Kyoung Jo, Quynh P. H. Nguyen, Dong Kong, Rachel Royfman, Anthony R. Cekic, Sushil Khanal, Ann L. Miller, Calvin Simerly, Gerald Schatten, Jadranka Loncarek, Vito Mennella, Tomer Avidor-Reiss   +12 more
doaj   +1 more source

A Bright Ratiometric Dipyrene Probe for Functional Imaging of Condensate Microenvironments in Living Cells

Advanced Science, Volume 13, Issue 54, 28 September 2026.
Ratiometric dipyrene imaging resolves monomer (M) and excimer (E) channels and computes pixel‐wise E/M maps within biomolecular condensates, yielding physicochemical fingerprints shaped by coupled polarity‐related solvation and microviscosity. These spatial fingerprints enable quantitative phenotyping of cellular states, exemplified by separation of ...
Koki Matsumoto, Sora Kitai, Yoshio Nishiyama, Shogo Amemori, Kei Makiyama, Dini Kurnia Ikliptikawati, Kentaro Ohira, Yuta Kozuka, Maho Tobita, Shih‐Cheng Chen, Chien‐Hung Yu, Wei‐Min Liu, De‐Chen Lin, Motohiro Mizuno, Kazuma Ogawa, Koichi Ogami, Kenji Takahashi, Hiroshi I. Suzuki, Richard W. Wong, Takahiro Soeta, Masaharu Hazawa   +20 more
wiley   +1 more source