Results 61 to 70 of about 20,027 (280)

Conserved molecular interactions in centriole-to-centrosome conversion. [PDF]

, 2015
Centrioles are required to assemble centrosomes for cell division and cilia for motility and signalling. New centrioles assemble perpendicularly to pre-existing ones in G1-S and elongate throughout S and G2.
A Grallert, A Rodrigues-Martins, Charlotte Mykura, CJ Tang, D Izquierdo, D Kitagawa, David M. Glover, EM Hatch, G Goshima, G Kohlmaier, G Lukinavicius, Giuliano Callaini, H Roque, H Varmark, Hélène Rangone, J Dobbelaere, J Fu, J Fu, J Gopalakrishnan, J Kleylein-Sohn, JE Sillibourne, Jennifer Chao-Chu, JH Sir, Jingyan Fu, K Kim, KF Sonnen, KF Sonnen, L Lau, M Bettencourt-Dias, M Bornens, M Hiraki, M Jerka-Dziadosz, M Martinez-Campos, M Ohta, M van Breugel, Marco Gottardo, Maria Giovanna Riparbelli, Mingwei Min, N Delgehyr, Nikola S. Dzhindzhev, NS Dzhindzhev, NS Dzhindzhev, O Cizmecioglu, R Habedanck, S Blachon, S Lawo, Sandra Schneider, SY Park, T Avidor-Reiss, TI Schmidt, TS Kim, V Mennella, V Mottier-Pavie, VJ Knorz, WJ Wang, YC Lin, Z Carvalho-Santos, Z Carvalho-Santos, Z Lipinszki, Z Lipinszki, ZA Novak, Zoltan Lipinszki   +61 more
core   +2 more sources

Re-examining the role of Drosophila Sas-4 in centrosome assembly using two-colour-3D-SIM FRAP

eLife, 2015
Centrosomes have many important functions and comprise a ‘mother’ and ‘daughter’ centriole surrounded by pericentriolar material (PCM). The mother centriole recruits and organises the PCM and templates the formation of the daughter centriole. It has been
Paul T Conduit, Alan Wainman, Zsofia A Novak, Timothy T Weil, Jordan W Raff   +4 more
doaj   +1 more source

Taking Down the Primary Cilium: Pathways for Disassembly in Differentiating Cells

BioEssays, EarlyView.
Primary cilia are developmentally essential subcellular signaling compartments. However, many differentiated cells lack primary cilia, and cilia disassembly in these tissue contexts has been largely overlooked. We highlight several pathways for primary cilia loss and examine how changes in ciliation states could contribute to diverse pathologies ...
Carolyn M. Ott, Saikat Mukhopadhyay
wiley   +1 more source

When the Clock Is Ticking: The Role of Mitotic Duration in Cell Fate Determination

BioEssays, EarlyView.
Recently, several studies identified mechanisms by which cells measure mitotic duration and how this influences cell fate, leading to normal cell cycle progression or G1 arrest. In light of drug‐resistant cancer cells that continue proliferating even after mitotic errors, understanding these mechanisms opens the door for new potential therapeutic ...
Cornelia Sala, Elmar Schiebel
wiley   +1 more source

Common themes in centriole and centrosome movements. [PDF]

, 2013
addresses: School of Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford, OX3 0BP, UK.Copyright © 2011 Elsevier. NOTICE: this is the author’s version of a work that was accepted for publication in Trends in Cell Biology.
Allen, Basto, Beisson, Boisvieux-Ulrich, Boisvieux-Ulrich, Boisvieux-Ulrich, Bornens, Brugerolle, Burakov, Carreno, Chevrier, Cowan, Cowan, Dammermann, Dawe, Dawe, Dawe, Desai, Dupin, Etienne-Manneville, Etienne-Manneville, Euteneuer, Fan, Feldman, Finetti, Goldstein, Gomes, Gonczy, Gray, Griffiths, Griffiths, Gull, Helen R. Dawe, Higginbotham, Hirota, Hong, Jenkins, Jolly, Jolly, Karsenti, Kemphues, Kim, Klotz, Koonce, Kuhn, Kunda, Kunda, Lemullois, Lemullois, Lin, Ludford-Menting, Magdalena, Mahoney, Malone, Manneville, Moreira-Leite, Nejmeddine, Nigg, Palazzo, Pan, Park, Park, Pegtel, Piel, Piguet, Prigozhina, Raff, Riento, Rios, Robinson, Robinson, Rosenblatt, Roux, Ryser, Salpingidou, Schmoranzer, Scholey, Siegrist, Sonneville, Starr, Stinchcombe, Stinchcombe, Stowers, Sue Vaughan, Tabuse, Tanaka, Thery, Toyoshima, Tsai, Tsai, Tsou, Valente, Vaughan, Walczak, Wiedemann, Woolner, Worman, Wright, Yamashita, Zhang, Zhang, Zhen   +101 more
core   +1 more source

Eugenia brasiliensis: Analysis of the Chemical Profile and Evaluation of Cytotoxic Potential

Chemistry &Biodiversity, EarlyView.
Leaves of Eugenia brasiliensis were dried, crushed and macerated with polarity increment. The antiporliferative and anti‐migratory potential and the cell cycle were evaluated. 28 compounds were tentatively identified by mass sceptrometry. ABSTRACT This work evaluated the antiproliferative potential of Eugenia brasiliensis leaf extracts against the HeLa
Giovana G. F. V. de Oliveira, Milena F. Longue, Letícia M. R. Pescinelli, Thiago S. Charret, Thalya S. R. Nogueira, Mariana T. M. Pereira, Ivo J. C. Vieira, Lucas S. Abreu, Vinicius D. B. Pascoal, Aislan C. R. F. Pascoal   +9 more
wiley   +1 more source

SnapShot: Centriole Biogenesis

Cell, 2009
SPD2 (Ce, Dm)/CEP192 (Hs)No centriole duplication (Ce);
Bettencourt-Dias, Mónica, Glover, David M.   +1 more
openaire   +4 more sources

Dynamics of centriole amplification in centrosome-depleted brain multiciliated progenitors

Scientific Reports, 2019
Reproductive and respiratory organs, along with brain ventricles, are lined by multiciliated epithelial cells (MCC) that generate cilia-powered fluid flows.
Olivier Mercey, Adel Al Jord, Philippe Rostaing, Alexia Mahuzier, Aurélien Fortoul, Amélie-Rose Boudjema, Marion Faucourt, Nathalie Spassky, Alice Meunier   +8 more
doaj   +1 more source

Meier–Gorlin syndrome and Wolf–Hirschhorn syndrome: two developmental disorders highlighting the importance of efficient DNA replication for normal development and neurogenesis [PDF]

, 2013
Microcephaly represents one of the most obvious clinical manifestations of impaired neurogenesis. Defects in the DNA damage response, in DNA repair, and structural abnormalities in centrosomes, centrioles and the spindle microtubule network have all been
Abramowicz, Iga, Carpenter, Gillian, Colnaghi, Rita, Kerzendorfer, Claudia, O'Driscoll, Mark   +4 more
core   +1 more source

Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly

Cytoskeleton, EarlyView.
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley   +1 more source