Results 11 to 20 of about 7,733 (159)
Centrioles without microtubules: a new morphological type of centriole [PDF]
Biology Open, 2018 The centrosome is the organizing center of microtubules in the cell, the basis for the origin of cilia and flagella and a site for the concentration of a regulatory proteins multitude.
Rustem Uzbekov +2 more
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Centrosomal JAK2 Tyrosine Kinase Regulates Primary Cilia Length, Cell Proliferation, and Cilia Orientation During Cell Migration. [PDF]
FASEB JGrowth hormone (GH) activates GHR at the primary cilium and stimulates centrosomal JAK2. JAK2 centrosomal localization requires both its SH2 domain and kinase activity. Cells expressing JAK2 variants deficient in centrosomal targeting show impaired control of cilia length, reduced proliferation, and cell migration compared with parental and JAK2 WT ...
Karki G +7 more
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Philosophical Transactions of the Royal Society B: Biological Sciences, 2014 Centrioles are among the largest protein-based structures found in most cell types, measuring approximately 250 nm in diameter and approximately 500 nm long in vertebrate cells. Here, we briefly review ultrastructural observations about centrioles and associated structures.
Winey, Mark, O'Toole, Eileen
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Molecular and Cellular Endocrinology, 2020 Centrioles are eukaryotic subcellular structures that produce and regulate massive cytoskeleton superstructures. They form centrosomes and cilia, regulate new centriole formation, anchor cilia to the cell, and regulate cilia function. These basic centriolar functions are executed in sperm cells during their amplification from spermatogonial stem cells ...
Tomer, Avidor-Reiss +2 more
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Atypical Centrioles During Sexual Reproduction
Frontiers in Cell and Developmental Biology, 2015 Centrioles are conserved, self-replicating, microtubule-based 9-fold symmetric subcellular organelles that are essential for proper cell division and function.
Tomer eAvidor-Reiss +3 more
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Centrioles and Ciliary Structures during Male Gametogenesis in Hexapoda: Discovery of New Models
Cells, 2020 Centrioles are-widely conserved barrel-shaped organelles present in most organisms. They are indirectly involved in the organization of the cytoplasmic microtubules both in interphase and during the cell division by recruiting the molecules needed for ...
Maria Giovanna Riparbelli +3 more
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Current Opinion in Structural Biology, 2021 Centrioles are microtubule-based structures involved in cell division and ciliogenesis. Centriole formation is a highly regulated cellular process and aberrations in centriole structure, size or numbers have implications in multiple human pathologies. In this review, we propose that the proteins that control centriole length can be subdivided into two ...
Ashwani, Sharma +2 more
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Frontiers in Cell and Developmental Biology, 2019 The precursor of the flagellar axoneme is already present in the primary spermatocytes of Drosophila melanogaster. During spermatogenesis each primary spermatocyte shows a centriole pair that moves to the cell membrane and organizes an axoneme-based ...
Veronica Persico +2 more
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Evolutionary conservation of centriole rotational asymmetry in the human centrosome
eLife, 2022 Centrioles are formed by microtubule triplets in a ninefold symmetric arrangement. In flagellated protists and animal multiciliated cells, accessory structures tethered to specific triplets render the centrioles rotationally asymmetric, a property that ...
Noémie Gaudin +11 more
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Interaction interface in the C-terminal parts of centriole proteins Sas6 and Ana2 [PDF]
Open Biology, 2020 The centriole is a ninefold symmetrical structure found at the core of centrosomes and, as a basal body, at the base of cilia, whose conserved duplication is regulated by Plk4 kinase.
Agnieszka Fatalska +3 more
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