Results 81 to 90 of about 74,831 (235)
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Experimental Physiology, EarlyView.Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
New insights into subcomplex assembly and modifications of centrosomal proteins
Cell Division, 2012 This review provides a brief overview of the recent work on centrosome proteomics, protein complex identification and functional characterization with an emphasis on the literature of the last three years.
Habermann Karin, Lange Bodo MH
doaj +1 more source
A study of the expression of germline-specific paralogs of the ubiquitously expressed NAC complex revealed their association with centrosomes [PDF]
, 2022 Elena A. Mikhaleva +7 more
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The Journal of Physiology, EarlyView.Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley +1 more source
TheToxoplasma gondiikinetochore is required for centrosome association with the centrocone (spindle pole) [PDF]
, 2013 Megan Farrell, Marc‐Jan Gubbels
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Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids
Advanced Science, Volume 13, Issue 4, 19 January 2026.Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang +6 more
wiley +1 more source
PLoS Genetics, 2016 Centrosomes are critical sites for orchestrating microtubule dynamics, and exhibit dynamic changes in size during the cell cycle. As cells progress to mitosis, centrosomes recruit more microtubules (MT) to form mitotic bipolar spindles that ensure proper
Michael D Stubenvoll +3 more
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Limiting Amounts of Centrosome Material Set Centrosome Size in C. elegans Embryos [PDF]
, 2011 Markus Decker +7 more
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Advanced Science, Volume 13, Issue 3, 14 January 2026.This study uncovers a previously unknown crosstalk between two major ubiquitin ligases, CRL5 and APC/C. The authors identify APC11 as a binding partner of CUL5, showing that their interaction regulates neddylation, substrate stability, and mitotic progression.
Danrui Cui +10 more
wiley +1 more source