Results 71 to 80 of about 459,917 (239)

Actividades físico-deportivas y daño cerebral adquirido

open access: yes, 2021
El presente documento recoge el resumen y las conclusiones de un taller sobre actividades físico-deportivas y daño cerebral adquirido (DCA). También para las personas con DCA, la práctica de actividades deportivas puede constituir un importante factor de
Federación Española de Daño Cerebral
core  

Multiscale Comparative Analyses of OVB-Organoids and Cerebral Organoids

open access: yesCells
Organoid technology is critical for studying human brain development, but existing single-organoid culture systems fail to simulate inter-organ interactions (e.g., optic vesicle–brain) in embryogenesis. This study aimed to establish a more comprehensive in vitro model for early neurodevelopment.
Jingyi Yang   +3 more
openaire   +2 more sources

Long Term Gene Expression in Human Induced Pluripotent Stem Cells and Cerebral Organoids to Model a Neurodegenerative Disease

open access: yesFrontiers in Cellular Neuroscience, 2020
Human brain organoids (mini-brains) consist of self-organized three-dimensional (3D) neural tissue which can be derived from reprogrammed adult cells and maintained for months in culture.
Ferid Nassor   +10 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Lung organoids: target cells for understanding respiratory diseases [PDF]

open access: yes, 2021
Human respiratory disease research currently lacks in vitro models that recapitulate most of the physiology and architecture of the lung. Furthermore, the complex composition and structure of the lung, as well as anatomical differences between humans and
Se-Ran Yang, Jooyeon Lee
core   +1 more source

Self-organization and applications of neural organoids

open access: yesEuropean Journal of Cell Biology
Organoid technology has become a field that attract many researcher’s attention and involvement. “Organoid” is a coined word which means organ like-tissue (Organ+oid), and organoid is determined as stem cell-derived three-dimensional (3D) tissues that ...
Hideya Sakaguchi
doaj   +1 more source

Recent Advances in Transparent Microelectrode Device Architecture and Fabrication Strategies for Biomedical Applications

open access: yesAdvanced Materials Technologies, EarlyView.
Transparent microelectrode arrays enable simultaneous optical and electrical electrophysiology with high spatiotemporal resolution, allowing multimodal observations of dynamic biological systems. Advances in materials and device architectures improve device performance by addressing key trade‐offs between optical transparency, impedance, and ...
Michael Abraham Listyawan   +6 more
wiley   +1 more source

Daño cerebral y familias. Atención psicológica a familias de personas con traumatismo craneoencefálico por accidentes de tráfico [PDF]

open access: yes, 2021
Cuando una persona sufre daño cerebral toda su red social se ve afectada, con especial intensidad su familia. Por eso esta guía es un documento muy visual y claro que será de mucha ayuda en el día a día de los familiares de personas con daño cerebral ...
Federación Española de Daño Cerebral
core  

Technical advances in pluripotent stem cell-derived and tumorigenic organoids [PDF]

open access: yes, 2022
Cell culture systems have been widely used to address fundamental questions in biology without sacrificing animals. Three-dimensional (3D) organoids provide more information on in vivo conditions than traditional culture systems because multiple cell ...
Eun Kyung Bong   +3 more
core   +1 more source

Quantifying differentiation of progenitor populations using cerebral organoid models for neurodevelopmental disorders. [PDF]

open access: yesSTAR Protoc
Summary: Neurodevelopmental disorders are characterized by complex phenotypes that often result from concomitant dysregulation of cell proliferation, differentiation, or other crucial developmental processes.
Schroder AL   +3 more
europepmc   +2 more sources

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