Results 141 to 150 of about 54,606 (348)

Synthesis and study of polyhydroxylated phenol derivatives with potential cosmetic and phytoiatric applications [PDF]

open access: yes, 2013
Tyrosinase (polyphenol oxidase, E.C. 1.14.18.1) and laccase (phenol oxidase, E.C. 1.10.3.2) are multifunctional copper-containing enzymes, that are keys in melanin biosynthesis, melanisation in animals and browning in plants.
Dallocchio, Roberto   +8 more
core  

Genistein induced by Frankliniella occidentalis feeding confers resistance to insect herbivores in peanut

open access: yesNew Plant Protection, EarlyView.
The Tianfu 22 (TF22) variety was identified as resistant to thrips based on field screening carried out over two consecutive years. Metabolomic profiling showed that thrip‐infested TF22 leaves exhibited differentially accumulated metabolites, particularly enriched in phenylpropanoid and secondary metabolite biosynthesis.
Qian Wang   +10 more
wiley   +1 more source

PPARγ Agonistic Activity of Mimulone and Diplacone Encapsulated in Liposomes and Cyclodextrin Complexes

open access: yesChemistryOpen, EarlyView.
Encapsulation of the geranylated flavanones mimulone and diplacone in hydroxypropyl‐β‐cyclodextrins (HP‐β‐CDs) and liposomes is evaluated for their peroxisome proliferator‐activated receptor gamma agonistic activity. While liposomes reduce efficacy, HP‐β‐CDs preserve up to 91.5% of mimulone's activity and mitigate diplacone's cytotoxicity, highlighting
Daniela Nykodýmová   +4 more
wiley   +1 more source

Synthesis of novel tris-chalcones and determination of their inhibition profiles against some metabolic enzymes

open access: yesArchives of Physiology and Biochemistry, 2019
In this study, we report the synthesis of novel tris-chalcones and testing of human carbonic anhydrase I, and II isoenzymes (hCA I, and hCA II), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and α-glycosidase (α-Gly) inhibitors for the ...
Serdar Burmaoglu   +5 more
semanticscholar   +1 more source

Synthesis, Anticancer Evaluation, and Molecular Docking of Novel Thiazolobenzimidazole–Thiazole Hybrids as Potent Colon Cancer Inhibitors

open access: yesChemistryOpen, EarlyView.
Novel benzimidazothiazole–thiazole hybrids are synthesized and evaluated for anticancer activity against HCT‐116 colon cancer cells. Compound 16b shows superior cytotoxicity over doxorubicin. Molecular docking confirms strong binding to 6MTU protein, and ADMET profiling indicates favorable pharmacokinetics and low toxicity.
Bader Huwaimel   +6 more
wiley   +1 more source

Osteogenic potential of different chalcones in an in vivo model: A preliminary study.

open access: yesJournal of Oral Research, 2017
Aim. To evaluate the osteogenic potential of chalcones using the rat critical size calvarial defect. Methods. The chalcones were synthesized from acetophenone following the Claisen-Schmidt aldol condensation method by varying the substituted ...
Xana Raquel Ortolan   +4 more
doaj   +1 more source

Chalcones and Flavanones Bearing Hydroxyl and/or Methoxyl Groups: Synthesis and Biological Assessments

open access: yesApplied Sciences, 2019
Chalcones and flavanones are isomeric structures and also classes of natural products, belonging to the flavonoid family. Moreover, their wide range of biological activities makes them key scaffolds for the synthesis of new and more efficient drugs.
G. Rosa   +4 more
semanticscholar   +1 more source

Functionality and Storage Evaluation of Fish Freshness Indicators Based on the Incorporation of Anthocyanins Extracted From Winery Grape Pomace Into Polyvinyl Alcohol/Starch Films

open access: yesPackaging Technology and Science, EarlyView.
Smart indicators were composed of polyvinyl alcohol and starch, infused with anthocyanins extracted from winery residues based on the solvent casting method. The developed films were characterised for microstructure integrity, water affinity properties and colour‐changing abilities.
Evgenia Basdeki   +5 more
wiley   +1 more source

University teaching of mass spectrometry as a key practical technique within the context of a fully integrated, spiral curriculum

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
Rationale Mass spectrometry (MS) is introduced to high school students in the UK in many pre‐university course syllabi. As such, we have identified the use of MS as a key technique that should be taught practically to undergraduates from the outset of their studies.
Andrew F. Worrall   +3 more
wiley   +1 more source

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