Results 11 to 20 of about 10,225 (206)

Progress of isolation, chemical synthesis and biological activities of natural chalcones bearing 2-hydroxy-3-methyl-3-butenyl group

Frontiers in Chemistry, 2022
Chalcones have a three-carbon α,β-unsaturated carbonyl system composed of two phenolic rings. Many chalcones have shown broad spectrum of biological activities with clinical potentials against various diseases.
Jiadai Zhai, Jiadai Zhai, Bingxia Sun, Feng Sang   +3 more
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Chalcone: A Promising Bioactive Scaffold in Medicinal Chemistry

Pharmaceuticals, 2022
Chalcones are a class of privileged scaffolds with high medicinal significance due to the presence of an α,β-unsaturated ketone functionality. Numerous functional modifications of chalcones have been reported, along with their pharmacological behavior ...
Gayathri Rajendran, Deepu Bhanu, Baladhandapani Aruchamy, Prasanna Ramani, Nanjan Pandurangan, Kondapa Naidu Bobba, Eun Jung Oh, Ho Yun Chung, Prakash Gangadaran, Byeong-Cheol Ahn   +9 more
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Structural, Vibrational and Electrochemical Analysis and Antibacterial Potential of Isomeric Chalcones Derived from Natural Acetophenone

Applied Sciences, 2020
Background: Chalcones are part of a family of small phenolic compounds that are being extensively studied for presenting a diversity of molecular structures and biological activities. In this paper, two chalcones, (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-
Priscila Teixeira da Silva, Thiago Sampaio de Freitas, Diniz Maciel Sena, Paulo Nogueira Bandeira, Murilo Ségio da Silva Julião, Emmanuel Silva Marinho, Ana Aline Coêlho Alcanfor, Emanuelle Machado Marinho, Pedro de Lima-Neto, Carlos Emídio Sampaio Nogueira, Henrique Douglas Melo Coutinho, Antonio Linkoln Alves Borges Leal, Humberto Medeiros Barreto, Natália Martins, Alexandre Magno Rodrigues Teixeira, Hélcio Silva dos Santos   +15 more
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Chalcone Scaffolds, Bioprecursors of Flavonoids: Chemistry, Bioactivities, and Pharmacokinetics

Molecules, 2021
Chalcones are secondary metabolites belonging to the flavonoid (C6-C3-C6 system) family that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant flavonoids.
Mithun Rudrapal, Johra Khan, Abdul Aziz Bin Dukhyil, Randa Mohammed Ibrahim Ismail Alarousy, Emmanuel Ifeanyi Attah, Tripti Sharma, Shubham Jagdish Khairnar, Atul Rupchand Bendale   +7 more
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Natural Chalcones and Derivatives in Colon Cancer: Pre-Clinical Challenges and the Promise of Chalcone-Based Nanoparticles

Pharmaceutics, 2023
Colon cancer poses a complex and substantial global health challenge, necessitating innovative therapeutic approaches. Chalcones, a versatile class of compounds with diverse pharmacological properties, have emerged as promising candidates for addressing ...
Soufyane Hba, Suzan Ghaddar, Hicham Wahnou, Aline Pinon, Riad El Kebbaj, Christelle Pouget, Vincent Sol, Bertrand Liagre, Mounia Oudghiri, Youness Limami   +9 more
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Advances in the Synthesis of Heteroaromatic Hybrid Chalcones

Molecules, 2023
Chalcones continue to occupy a venerated status as scaffolds for the construction of a variety of heterocyclic molecules with medicinal and industrial properties. Syntheses of hybrid chalcones featuring heteroaromatic components, especially those methods
Ajay Mallia, Joseph Sloop
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Synthesis, molecular docking and biochemical analysis of aminoalkylated naphthalene-based chalcones as acetylcholinesterase inhibitors

Journal of Taibah University for Science, 2021
Twelve novel chalcones were synthesized using 2-alkyloxy-naphthaldehydes and Mannich bases of 4-hydroxyacetophenone. The chalcones were characterized using FTIR, 1D and 2D NMR and HRMS spectroscopy.
Ghadah Aljohani, Adeeb Al-Sheikh Ali, Shaya Y. Alraqa, Syazwani Itri Amran, Norazah Basar   +4 more
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The solubility and stability of heterocyclic chalcones compared with trans-chalcone [PDF]

Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials, 2020
Heterocyclic chalcones are a recently explored subgroup of chalcones that have sparked interest due to their significant antibacterial and antifungal capabilities. Herein, the structure and solubility of two such compounds, (E)-1-(1H-pyrrol-2-yl)-3-(thiophen-2-yl)prop-2-en-1-one and (E)-3-phenyl-1-(1H-pyrrol-2-yl)prop-2-en-1-one, are assessed.
Stephen G. Sweeting, Charlie L. Hall, Jason Potticary, Natalie E. Pridmore, Stephen D. Warren, Matthew E. Cremeens, Gemma D. D'Ambruoso, Masaomi Matsumoto, Simon R. Hall   +8 more
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Recent Advances in bis-Chalcone-Based Photoinitiators of Polymerization: From Mechanistic Investigations to Applications

Molecules, 2021
Over the past several decades, photopolymerization has become an active research field, and the ongoing efforts to develop new photoinitiating systems are supported by the different applications in which this polymerization technique is involved ...
Nicolas Giacoletto, Frédéric Dumur
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Determination of the lipophilicity of 2'-hydroxychalcones by RP HPLC method [PDF]

Hemijska Industrija, 2016
Lipophilicity of twelve synthesized chalcones, whose ring B is a ortho, meta or para monosubstituted with alkyl, oxyalkyl groups or halogens was determined by reverse phase liquid chromatography, using octadecyl-functionalized (RP-18) silica gel
Bašić Jasmina V., Ivković Branka M., Stevanović Slavica, Lazarević Anđelka, Vujić Zorica B.   +4 more
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