Results 251 to 260 of about 2,601,570 (295)

TRP Channel Antagonists as Potential Antitussives

Lung, 2011
Cough is a troublesome symptom associated with many respiratory diseases. In some instances cough can become prolonged and excessive, and chronic cough of various aetiologies is a common presentation to specialist respiratory clinics. However, current treatment options are limited.
Megan S, Grace, Eric, Dubuis, Mark A, Birrell, Maria G, Belvisi   +3 more
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Interatomic potential and channelling

Radiation Effects, 1976
Abstract An interatomic potential proposed recently in connection with some planar channelling calculations has been examined with regards to its predictions for the quantities of interest in axial channeling, such as string potential and critical angles.
openaire   +1 more source

Potential Proton‐Release Channels in Bacteriorhodopsin

ChemPhysChem, 2008
AbstractThe protein bacteriorhodopsin pumps protons across a bacterial membrane; its pumping cycle is triggered by the photoisomerization of a retinal cofactor and involves multiple proton‐transfer reactions between intermittent protonation sites. These transfers are either direct or mediated by hydrogen‐bonded networks, which may include internal ...
Alain, Chaumont, Marcel, Baer, Gerald, Mathias, Dominik, Marx   +3 more
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Channel potential and channel width in narrow buried-channel MOSFET's

IEEE Transactions on Electron Devices, 1984
A new method is described for determining the effective width over which incremental charge spreads in a narrow buried-channel transistor. The method is based on the transconductance in the buried-channel mode. Experimental results for effective widths and channel potential shifts are presented for MOSFET's with effective channel widths from 2 to 10 µm.
B.C. Burkey, G. Lubberts, E.A. Trabka, T.J. Tredwell   +3 more
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Potential Flow in Channels

SIAM Journal on Scientific and Statistical Computing, 1990
A method is presented for calculating potential flows in infinite channels. Given a collection of N sources in the channel and a zero normal flow boundary condition, the method requires an amount of work proportional to N to evaluate the induced velocity field at each source position.
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Many-Channel Bargmann Potentials

Journal of Mathematical Physics, 1964
A generalization of the Bargmann potentials to include the case of nonrelativistics-wave scattering of a particle by a target having a finite number of discrete excited states is presented. This generalization allows the explicit construction of a large class of many-channel S-matrices meromorphic on their energy Riemann surfaces as well as the ...
openaire   +1 more source

Single-channel currents through transient-receptor-potential-like (TRPL) channels

Pflügers Archiv - European Journal of Physiology, 2000
Single-channel current recordings were used to examine the properties and modulation of Drosophila transient-receptor-potential-like (TRPL) channels transiently expressed in HEK and COS cells. Recombinant TRPL channels were constitutively active and characterized by a conductance of 104 pS in on-cell membrane patches with 115 mM Na+ and 2 mM Mg2+ in ...
J, Hambrecht, S, Zimmer, V, Flockerzi, A, Cavalié   +3 more
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Transient Receptor Potential Channels

2011
Volume 696 SOFTWARE TOOLS AND ALGORITHMS FOR BIOLOGICALSYSTEMSEdited by Hamid R. Arabnia and Quoc-Nam TranVolume 697 HOT TOPICS IN INFECTION AND IMMUNITY IN CHILDREN VIIEdited by Andrew Pollard, Adam Finn, and Nigel CurtisVolume 698 BIO-FARMS FOR NUTRACEUTICALS: FUNCTIONAL FOODAND SAFETY CONTROL BY BIOSENSORSMaria Teresa Giardi, Giuseppina Rea and ...
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Ion Channels in Action Potential Generation

Hospital Practice, 1992
Molecular structure-function studies have identified the two key regions--the voltage sensor and pore--of the sodium and potassium channels responsible for the action potential in nerve axon. Mutational analysis has focused on the amino acids that are most important in each region. Similar studies in myocytes and nerve cell bodies are now being pursued.
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TRP Channels as Potential Drug Targets

Annual Review of Pharmacology and Toxicology, 2018
The transient receptor potential (TRP) superfamily of channels comprises a diverse group of cation channels. Four TRP channel subunits coassemble to form functional homo- or heterotetramers that pass sodium, calcium, or both in the inward direction. Modulating TRP channel activity provides an important way to impact cellular function by regulating both
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