Transient Receptor Potential Cation Channels in Disease [PDF]
Physiological Reviews, 2007 The transient receptor potential (TRP) superfamily consists of a large number of cation channels that are mostly permeable to both monovalent and divalent cations. The 28 mammalian TRP channels can be subdivided into six main subfamilies: the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystin), TRPML (mucolipin), and the TRPA ...
Nilius, Bernd +3 more
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Structural basis of TRPC4 regulation by calmodulin and pharmacological agents
eLife, 2020 Canonical transient receptor potential channels (TRPC) are involved in receptor-operated and/or store-operated Ca2+ signaling. Inhibition of TRPCs by small molecules was shown to be promising in treating renal diseases.
Deivanayagabarathy Vinayagam +11 more
doaj +1 more source
Genomic organization and chromosomal localization of the murine 2 P domain potassium channel gene Kcnk8: conservation of gene structure in 2 P domain potassium channels. [PDF]
, 2000 A 2 P domain potassium channel expressed in eye, lung, and stomach, Kcnk8, has recently been identified. To initiate further biochemical and genetic studies of this channel, we assembled the murine Kcnk8 cDNA sequence, characterized the genomic structure
Bockenhauer, D +4 more
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eLife, 2017 Small conductance calcium-activated potassium channels (SK channels) are present in spines and can be activated by backpropagating action potentials (APs).
Scott L Jones +2 more
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Deciphering the Role of Ion Channels in Early Defense Signaling against Herbivorous Insects
Cells, 2021 Plants and insect herbivores are in a relentless battle to outwit each other. Plants have evolved various strategies to detect herbivores and mount an effective defense system against them.
Akanksha Gandhi +5 more
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Blockade of current through single calcium channels by trivalent lanthanide cations. Effect of ionic radius on the rates of ion entry and exit. [PDF]
, 1990 Currents flowing through single dihydropyridine-sensitive Ca2+ channels were recorded from cell-attached patches on C2 myotubes. In the presence of dihydropyridine agonist to prolong the duration of single-channel openings, adding micromolar ...
Lansman, JB
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Retention Characteristics and DMP Efficiency in V-NAND With Dimple Structure
IEEE Journal of the Electron Devices SocietyIn this paper, we analyze the retention characteristics of vertical NAND(V-NAND) with dimpled (convex and concave) structures considering the impact of adjacent cell states.
Seongwoo Kim +3 more
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Open Medicine, 2023 Heroin can cause damage to many human organs, possibly leading to different types of arrhythmias and abnormal electrophysiological function of the heart muscle and the steady state of calcium-ion channels.
Su Liping +12 more
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Thermo-sensitive TRP channels and prevention of major chronic diseases
Di-san junyi daxue xuebao, 2022 American scientists David Julius and Ardem Patapoutian won the Nobel Prize in physiology or medicine in 2021 for their groundbreaking discoveries of capsaicin receptor TRPV1 and menthol receptor TRPM8, revealing the secrets of temperature perception. The
ZHU Zhiming, LIU Daoyan
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Neutron-proton scattering and singular potentials
, 2018 We consider a Bargmann-type rational parametrization of the nucleon scattering phase shifts. Applying Marchenko's method of quantum inverse scattering we show that the scattering data suggest a singular repulsive core of the potential of the form $2/r^2$
Balog, Janos +2 more
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