Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Protein Energy Malnutrition is a public health challenge that negatively affects young children in developing countries. Formulation of foods fortified with edible insects is a potentially sustainable approach to increase the protein quality in the diet ...
Amos Kipkemoi Ronoh +3 more
doaj +1 more source
Comparison of Check-All-That-Apply (CATA), Rate-All-That-Apply (RATA), Flash Profile, Free Listing, and Conventional Descriptive Analysis for the Sensory Profiling of Sweet Pumpkin Porridge. [PDF]
Kim D, Kwak H, Lim M, Lee Y.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Discrimination Ability of Assessors in Check-All-That-Apply Tests: Method and Product Development. [PDF]
Gere A, Bajusz D, Biró B, Rácz A.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Use of Focus Group as Selection Method of Descriptors for Check-All-That-Apply (CATA) for Sensory Characteristics of Hot Dogs. [PDF]
Rodrigues I, Magalhaes DR, Trindade MA.
europepmc +1 more source
Überblick Bundestag Jugend-Check zum Entwurf eines Berufsbildungsvalidierungs- und -digitalisierungsgesetzes (BVaDiG) (Kabinettsbefassung: 07.02.2024) [PDF]
Der „Überblick Bundestag“ wird bei Jugend-Checks erstellt, bei welchen der Gesetzentwurf in der Kabinettsfassung vorliegt. Das bedeutet, dass dieser Gesetzentwurf in der vorliegenden Fassung im Bundestag diskutiert werden wird.
Kompetenzzentrum Jugend-Check
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Überblick Bundestag Jugend-Check zum Entwurf eines Gesetzes zur Beschäftigungssicherung infolge der COVID-19-Pandemie (Beschäftigungssicherungsgesetz – BeschSiG) (Kabinettsfassung: 16.09.2020) [PDF]
Der „Überblick Bundestag“ wird bei Jugend-Checks erstellt, bei welchen der Gesetzentwurf in der Kabinettsfassung vorliegt. Das bedeutet, dass dieser Gesetzentwurf in der vorliegenden Fassung im Bundestag diskutiert werden wird.
Kompetenzzentrum Jugend-Check
core

