Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Überblick Bundestag Jugend-Check zum Entwurf eines Zweiten Gesetzes zur Änderung des Schwangerschaftskonfliktgesetzes (Kabinettsbefassung: 24.01.2024) [PDF]
Der „Überblick Bundestag“ wird bei Jugend-Checks erstellt, bei welchen der Gesetzentwurf in der Kabinettsfassung vorliegt. Das bedeutet, dass dieser Gesetzentwurf in der vorliegenden Fassung im Bundestag diskutiert werden wird.
Kompetenzzentrum Jugend-Check
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
: As public concern over the potential health risks associated with high-fat diets intensifies, the market for low-fat dairy is experiencing a surge in demand.
Xuelu Chi +9 more
doaj +1 more source
Check-All-That-Apply (CATA) Test to Investigate the Consumers' Perception of Olive Oil Sensory Properties: Effect of Storage Time and Packaging Material. [PDF]
Piochi M, Cabrino G, Torri L.
europepmc +1 more source
Überblick Bundestag Jugend-Check zum Entwurf eines Steueränderungsgesetzes 2025 (Kabinettsbefassung: 10.09.2025) [PDF]
Der „Überblick Bundestag“ wird bei Jugend-Checks erstellt, bei welchen der Gesetzentwurf in der Kabinettsfassung vorliegt. Das bedeutet, dass dieser Gesetzentwurf in der vorliegenden Fassung im Bundestag diskutiert werden wird.
Kompetenzzentrum Jugend-Check
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Combination of the Check-All-That-Apply (CATA) Method and Just-About-Right (JAR) Scale to Evaluate Korean Traditional Rice Wine (Yakju). [PDF]
Lee S, Kwak HS, Kim SS, Lee Y.
europepmc +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Warmed-over flavour profiles, microbial changes, shelf-life and check-all-that-apply sensory analysis of cooked minced pork treated with varying levels of Moringa oleifera leaf and root powder. [PDF]
N S L, A J A, E M I.
europepmc +1 more source

