Results 21 to 30 of about 86,546 (282)

Induction of angiogenic chemokine CCL2 by human herpesvirus 8 chemokine receptor

Virology, 2010
Human herpesvirus 8 (HHV-8) is associated with Kaposi's sarcoma (KS), an endothelial cell lesion believed to be initiated and driven primarily by cytokine dysregulation. Among the viral proteins suspected as contributing to viral pathogenesis is the lytically expressed viral G protein-coupled receptor (vGPCR), which can induce various cellular ...
Choi, Young Bong, Nicholas, John
openaire   +2 more sources

Natural Killer T Cells Infiltrate Neuroblastomas Expressing the Chemokine CCL2 [PDF]

The Journal of Experimental Medicine, 2004
CD1d-restricted Vα24-Jα18–invariant natural killer T cells (iNKTs) are potentially important in tumor immunity. However, little is known about their localization to tumors. We analyzed 98 untreated primary neuroblastomas from patients with metastatic disease (stage 4) for tumor-infiltrating iNKTs using TaqMan® reverse transcription polymerase chain ...
Metelitsa, Leonid S., Wu, Hong-Wei, Wang, Hong, Yang, Yujun, Warsi, Zamir, Asgharzadeh, Shahab, Groshen, Susan, Wilson, S. Brian, Seeger, Robert C.   +8 more
openaire   +2 more sources

Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system. [PDF]

, 2006
Encounters with neurotropic viruses result in varied outcomes ranging from encephalitis, paralytic poliomyelitis or other serious consequences to relatively benign infection.
A. Meyer, A.A. Dandekar, A.D. Luster, B. Mehrad, B. Parra, B. Parra, B.D. Pearce, B.P. Chen, B.T. Fife, C. Gerard, C. Ramakrishna, C. Ramakrishna, C.A. Biron, C.E. Patterson, C.J. Raport, C.M. Hogaboam, D. Franciotta, D. Galimberti, D. Whiting, D.D. Taub, D.J. Mahad, D.M. Muller, D.N. Cook, D.P. Widney, E. Lazzeri, E.J. McMahon, F.R. Fischer, F.S. Cheever, G. Penna, G. Penna, G.B. Huffnagle, G.C. Hildebrandt, G.F. Wu, H. Bartosik-Psujek, H.G. Fischer, H.G. Fischer, I. Banisor, I. Clark-Lewis, I. Salomon, I. Tsunoda, I.E. Flesch, J. Gosling, J.B. Domachowske, J.C. Houck, J.F. Bazan, J.H. Dufour, J.H. Xie, J.J. Phillips, J.M. Farber, J.S. Haring, J.S. Haring, J.S. Williamson, J.S. Williamson, K. Holmes, K. McIntosh, K.E. Balashov, K.S. Held, K.S. Warmington, K.V. Holmes, L. Boring, L. Boring, L. Cartier, L. Gu, L. Gu, L. Pewe, L. Pewe, M. Baggiolini, M. Greter, M. Matsui, M.A. Olszewski, M.J. Buchmeier, M.J. Trifilo, M.J. Trifilo, M.J. Trifilo, M.M. Lai, M.T. Lin, M.T. Lin, M.T. Liu, M.T. Liu, M.T. Liu, N. Sato, N.J. Megjugorac, N.W. Marten, R. Gade-Andavolu, R. Watanabe, R.F. Castro, R.S. Klein, S. Narumi, S. Qin, S. Xue, S.A. Stohlman, S.A. Stohlman, S.D. Miller, S.M. Stamatovic, S.R. Perlman, T.E. Lane, T.E. Lane, T.E. Lane, T.L. Sorensen, T.L. Sorensen, T.S. Kim, T.S. Kim, W.G. Glass, W.G. Glass, W.G. Glass, W.G. Glass, W.J. Karpus, Y. Zhang, Y. Zhou   +108 more
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The RNA-binding protein IMP2 drives a stromal-Th17 cell circuit in autoimmune neuroinflammation

JCI Insight, 2022
Stromal cells are emerging as key drivers of autoimmunity, partially because they produce inflammatory chemokines that orchestrate inflammation. Chemokine expression is regulated transcriptionally but also through posttranscriptional mechanisms, the ...
Rami Bechara, Nilesh Amatya, Saikat Majumder, Chunsheng Zhou, Yang Li, Qixing Liu, Mandy J. McGeachy, Sarah L. Gaffen   +7 more
doaj   +1 more source

Questions about Chemokine and Chemokine Receptor Antagonism in Renal Inflammation [PDF]

, 2010
Chemokines remain attractive therapeutic targets for modulating inflammatory diseases in all areas of medicine including acute and chronic kidney disease.
Anders, Hans-Joachim, Sayyed, Sufyan Ali, Vielhauer, Volker   +2 more
core   +1 more source

Predictive value of CCL2 in the prognosis and immunotherapy response of glioblastoma multiforme

BMC Genomics, 2023
Background Glioblastoma multiforme (GBM) is the most common and lethal primary brain tumor with a poor prognosis. The C-C motif chemokine ligand 2 (CCL2) has shown abnormal expression associated with progression of multiple malignancies, however, its ...
Longfei Deng, Jie Ren, Benqin Li, Yinggang Wang, Nianfen Jiang, Yi Wang, Hongjuan Cui   +6 more
doaj   +1 more source

CCL2 promotes osteogenesis by facilitating macrophage migration during acute inflammation

Frontiers in Cell and Developmental Biology, 2023
Novel minimally invasive strategies are needed to obtain robust bone healing in complex fractures and bone defects in the elderly population. Local cell therapy is one potential option for future treatment.
Masakazu Toya, Ning Zhang, Ning Zhang, Masanori Tsubosaka, Junichi Kushioka, Qi Gao, Xueping Li, Simon Kwoon-Ho Chow, Stuart B. Goodman, Stuart B. Goodman   +9 more
doaj   +1 more source

A dose-dependent plasma signature of the safety and immunogenicity of the rVSV-Ebola vaccine in Europe and Africa. [PDF]

, 2017
The 2014-2015 Ebola epidemic affected several African countries, claiming more than 11,000 lives and leaving thousands with ongoing sequelae. Safe and effective vaccines could prevent or limit future outbreaks.
Agnandji, ST, Brosnahan, J, Combescure, C, Dayer, J-A, Grillet, S, Haks, MC, Harandi, AM, Huttner, A, Kaiser, L, Kremsner, PG, Medaglini, D, Modoux, C, Monath, T, Ottenhoff, THM, Quinten, E, Roux-Lombard, P, Siegrist, C-A, VEBCON and VSV-EBOVAC Consortia   +17 more
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CXCL10 ( ) and CCL2 ( ) chemokines in systemic sclerosis a longitudinal study [PDF]

Rheumatology, 2008
To measure serum levels of CXCL10 and CCL2 chemokines in patients with SSc, and relate the findings to clinical phenotype and disease progression.Serum CXCL10 and CCL2 were assayed in 72 consecutive newly diagnosed SSc patients and in 72 sex- and age-matched controls. In 37 SSc and 37 controls, serum CXCL10 and CCL2 were re-evaluated 5 yrs later.SSc at
ANTONELLI, ALESSANDRO, Ferri C, Fallahi P, Ferrari SM, Giuggioli D, Colaci M, Manfredi A, Frascerra S, FRANZONI, FERDINANDO, GALETTA, FABIO, FERRANNINI, ELEUTERIO   +10 more
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Chemokine profiles of interstitial pneumonia in patients with dermatomyositis: a case control study

Scientific Reports, 2017
Chemokines play an important role in the pathophysiology of dermatomyositis (DM) with interstitial pneumonia (IP). However, the relation between chemokines and the disease activity or prognosis of DM-IP has not been elucidated. We evaluated the serum C-C
Katsuhiro Oda, Takuya Kotani, Tohru Takeuchi, Takaaki Ishida, Takeshi Shoda, Kentaro Isoda, Shuzo Yoshida, Yasuichiro Nishimura, Shigeki Makino   +8 more
doaj   +1 more source