Results 111 to 120 of about 68,540 (230)

ELR positive CXCL chemokines are highly expressed in an animal model of ulcerative colitis

Journal of Inflammation Research, 2019
Mohammad Amin Boshagh,1,2 Poorya Foroutan,1,2 Mohammad Raman Moloudi,3 Shohreh Fakhari,1 Parisa Malakouti,1 Bahram Nikkhoo,1 Ali Jalili1,21Cancer and Immunology Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran; 2Department of ...
Boshagh MA, Foroutan P, Moloudi MR, Fakhari S, Malakouti P, Nikkhoo B, Jalili A   +6 more
doaj  

The role of chemokines in Schistosoma mansoni infection: insights from human disease and murine models

Memorias do Instituto Oswaldo Cruz, 2006
Chemokines are a superfamily of low-molecular-weight cytokines that were initially described for their chemoattractant activity. It is now clear chemokines have several other activities that modulate immune processes.
Adriano LS Souza, Silvio R Sousa-Pereira, Mauro M Teixeira, José R Lambertucci, Antonio L Teixeira   +4 more
doaj   +1 more source

Chemokines from a Structural Perspective

, 2017
Chemokines are a family of small, highly conserved cytokines that mediate various biological processes, including chemotaxis, hematopoiesis, and angiogenesis, and that function by interacting with cell surface G-Protein Coupled Receptors (GPCRs). Because
Kevin Mayo, Michelle Miller
core   +1 more source

Immune cells in the pathogenesis of abdominal aortic aneurysm: Roles, regulation and targeted interventions

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review provides a comprehensive overview of how macrophages, neutrophils, T cells and other immune cells infiltrate the aortic wall, undergo phenotypic shifts and interact with one another in abdominal aortic aneurysm (AAA). Background Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease with no approved clinical drugs. Immune
Junqi Peng, Hanqing Zhang, Yun Wu, Song Chen   +3 more
wiley   +1 more source

CXC chemokines generate age-related increases in neutrophil-mediated brain inflammation and blood-brain barrier breakdown.

, 1998
Children are at greater risk than adults of permanent brain damage and mortality following head injury or infection [1-5]. Rodent models have demonstrated a 'window of susceptibility' in young animals during which the brain parenchyma is at greater risk ...
Wells, G, Clements, J, Fearn, S, Dempster, R, Walker, K, Perry, VH, Anthony, D   +6 more
core   +1 more source

The proinflammatory CXC-chemokines GRO-alpha/CXCL1 and MIG/CXCL9 are concomitantly expressed in ulcerative colitis and decrease during treatment with topical corticosteroids

, 2007
Background Ulcerative colitis is characterized by relapsing mucosal inflammation where the lesions include tissue-damaging granulocytes. In addition, T cells and natural killer (NK) cells play important pathophysiologic roles.
Marie Carlson, Bjartell, Anders, Carlson, Marie, Arne Egesten, Sangfelt, Per,, Egesten, Arne, Carlson, Marie,, Mette Eliasson, Erjefält, Jonas S., Anders I. Olin, Olin, Anders, Anders Bjartell, Jonas S. Erjefält, Eliasson, Mette, Erjefält, Jonas, Olin, Anders I., Sangfelt, Per, Per Sangfelt, Erjefält, Jonas,, Olin, Anders,, Egesten, Arne,, Bjartell, Anders,, Lund University., Eliasson, Mette,   +23 more
core   +1 more source

Pulsed Focused Ultrasound–Mediated Mechanopriming Enhances the Therapeutic Efficacy of Mesenchymal Stromal Cell–Derived Extracellular Vesicles in Acute Respiratory Distress Syndrome

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
ABSTRACT Extracellular vesicles (EVs) derived from mesenchymal stem or stromal cells (MSCs) have shown therapeutic potential for acute respiratory distress syndrome (ARDS), yet reproducible and scalable methods to enhance EV yield and therapeutic potency remain limited.
Shashank Chetty, Shobha Regmi, Abantika Ganguly, Reza Yarani, Fantahun Biadglegne Degeneh, Rosita Primavera, Jing Wang, Avnesh S. Thakor   +7 more
wiley   +1 more source

Pro-inflammatory cytokines and CXC chemokines as game-changer in age-associated prostate cancer and ovarian cancer: Insights from preclinical and clinical studies' outcomes

Pharmacological Research
Prostate cancer (PC) and Ovarian cancer (OC) are two of the most common types of cancer that affect the reproductive systems of older men and women. These cancers are associated with a poor quality of life among the aged population.
Amin Ullah, Yongxiu Chen, Rajeev K. Singla, Dan Cao, Bairong Shen   +4 more
doaj   +1 more source

Knockdown of CLEC7A Alleviates Ischemic Brain Injury by an Anti‐Inflammatory Microglial Phenotype via the CXCL1/CXCR2 Axis

Journal of Neuroscience Research, Volume 104, Issue 10, October 2026.
Integrated bioinformatics analysis of GEO datasets identified CLEC7A as a key hub gene in ischemic stroke. In vitro (OGD model with BV2 microglia/HT22 neuron co‑culture) and in vivo (rat MCAO model) experiments demonstrated that CLEC7A knockdown reduced apoptosis, suppressed inflammation, decreased infarct size, and attenuated brain injury ...
Min Xi, Meipin Yang, Tianyi Xu, Chunhua Yun, Hui Lu, Zhenqiang Zhao, Jiying Li, Jijun Li, Yingting Fu, Yunyu Li, Wei Li   +10 more
wiley   +1 more source

Mycobacterium bovis bacillus Calmette–Guérin (BCG) induces human CC- and CXC-chemokines in vitro and in vivo

, 2006
Summary Both CC- and CXC-chemokines are known to be potent leucocyte activators and chemoattractants and play important roles in inflammatory responses.
Y Luo, X Chen, M A O'Donnell
core   +1 more source