Results 21 to 30 of about 68,540 (230)
Memorias do Instituto Oswaldo Cruz, 2009 Chemokines recruit and activate leukocytes, assisting granuloma formation. Herein, we evaluated plasma chemokines in patients with active tuberculosis (ATB) and after completing treatment (TTB) and compared them to BCG-vaccinated healthy controls (HC ...
Caroline de Souza Almeida +5 more
doaj +2 more sources
CXC chemokines in angiogenesis [PDF]
Cytokine & Growth Factor Reviews, 2005 CXC chemokines display pleiotropic effects in immunity, regulating angiogenesis, and mediating organ-specific metastases of cancer. In the context of angiogenesis, CXC chemokines are a unique family of cytokines, known for their ability to behave in a disparate manner in the regulation of angiogenesis.
Robert M, Strieter +4 more
openaire +3 more sources
Prognostic Significance and Immune Cell Infiltration Analysis of CXC Chemokines in Glioblastoma
Zhongliu Fangzhi Yanjiu, 2021 Objective To analyze the expression of CXC chemokines in glioblastoma (GBM), and investigate their prognostic value and potential roles as therapeutic targets. Methods Differential expression and prognostic value of CXC chemokines in GBM were obtained in
LIU Fangyuan, SU Xiulan
doaj +1 more source
ELR+ CXC chemokine signalling in cartilage homeostasis. [PDF]
, 2011 PhDThe production of ELR+ CXC chemokines is widely studied in arthritis and has been postulated to contribute to the inflammatory phenomena that eventually lead to cartilage breakdown.
Sherwood, Joanna
core +4 more sources
Frontiers in Cell and Developmental Biology, 2023 Diabetes-related pathophysiological alterations and various female reproductive difficulties were common in pregnant women with gestational diabetes mellitus (GDM), who had 21.1 million live births.
Amin Ullah +4 more
doaj +1 more source
Frontiers in Oncology, 2021 BackgroundPancreatic cancer is one of the principal causes of tumor-related death worldwide. CXC chemokines, a subfamily of functional chemotactic peptides, affect the initiation of tumor cells and clinical outcomes in several human malignant tumors ...
Jiacheng Huang +9 more
doaj +1 more source
BMC Medical Genomics, 2022 Background The prognosis of pancreatic cancer is poor, with a 5-year survival rate of less than 10%. Studies have shown that chemokines in the tumour microenvironment are often altered, which is associated with immune infiltration and the prognosis and ...
Yanhua Jing +3 more
doaj +1 more source
Cancer Cell International, 2021 Background The tumor microenvironment (TME) has received an increasing amount of attention. CXC chemokines can regulate immune cell transport and tumor cell activity to exert anti-tumor immunity.
Weina Kong +7 more
doaj +1 more source
Evasins: Biology and Therapeutic Potential of Broad-Spectrum Chemokine Inhibitors. [PDF]
Basic Clin Pharmacol ToxicolABSTRACT Ticks are haematophagous parasites that rely on uninterrupted bloodmeals for survival and need an effective strategy to suppress the host inflammatory response. Leukocyte recruitment is a chemokine‐mediated hallmark of inflammation, which ticks counteract via anti‐chemokine proteins in their saliva named evasins.
Bialek EL +3 more
europepmc +2 more sources
Hepatology, EarlyView., 2022 Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim +12 more
wiley +1 more source