Results 31 to 40 of about 597,477 (331)
Autism with intellectual disability is associated with increased levels of maternal cytokines and chemokines during gestation. [PDF]
, 2016 Immune abnormalities have been described in some individuals with autism spectrum disorders (ASDs) as well as their family members. However, few studies have directly investigated the role of prenatal cytokine and chemokine profiles on neurodevelopmental
Ashwood, P +10 more
core +2 more sources
Multiple Roles for Chemokines in Neutrophil Biology
Frontiers in Immunology, 2020 Chemokines are recognized as the most critical mediators for selective neutrophil recruitment during inflammatory conditions. Furthermore, they are considered fundamental regulators of neutrophil mobilization from the bone marrow (BM) to the bloodstream ...
A. Capucetti, F. Albano, R. Bonecchi
semanticscholar +1 more source
Frontiers in Immunology, 2012 Chemoattractant cytokines or chemokines constitute a family of structurally related proteins found in vertebrates, bacteria or viruses. So far, 48 chemokines genes have been identified in humans, which bind to around 20 chemokine receptors.
Xavier eBLANCHET +4 more
doaj +1 more source
The Roles of Stroma-Derived Chemokine in Different Stages of Cancer Metastases
Frontiers in Immunology, 2020 The intricate interplay between malignant cells and host cellular and non-cellular components play crucial role in different stages of tumor development, progression, and metastases.
Shahid Hussain +8 more
doaj +1 more source
A homeostatic function of CXCR2 signalling in articular cartilage [PDF]
, 2014 Funding This work was funded by Arthritis Research UK (grants 17859, 17971, 19654), INNOCHEM EU FP6 (grant LSHB-CT-2005-51867), MRC (MR/K013076/1) and the William Harvey Research FoundationPeer reviewedPublisher ...
Aberdeen +17 more
core +3 more sources
Cooperative Stimulation of Dendritic Cells by Cryptococcus neoformans Mannoproteins and CpG Oligodeoxynucleotides [PDF]
, 2008 While mannosylation targets antigens to mannose receptors on dendritic cells (DC), the resultant immune response is suboptimal. We hypothesized that the addition of toll-like receptor (TLR) ligands would enhance the DC response to mannosylated antigens ...
Dan, Jennifer M. +3 more
core +8 more sources
Targeting Chemokine—Glycosaminoglycan Interactions to Inhibit Inflammation
Frontiers in Immunology, 2020 Leukocyte migration into tissues depends on the activity of chemokines that form concentration gradients to guide leukocytes to a specific site. Interaction of chemokines with their specific G protein-coupled receptors (GPCRs) on leukocytes induces ...
Helena Crijns +2 more
doaj +1 more source
Chemokines and Chemokine Receptors: New Targets for Cancer Immunotherapy
Frontiers in Immunology, 2019 Immunotherapy is a clinically validated treatment for many cancers to boost the immune system against tumor growth and dissemination. Several strategies are used to harness immune cells: monoclonal antibodies against tumor antigens, immune checkpoint ...
Valeria Mollica Poeta +3 more
semanticscholar +1 more source
The Scientific World Journal, 2007 Chemokines are a family of polypeptides that direct the migration of leukocytestoward a site of infection. They play a major role in autoimmune disease and chemokine receptors have recently been found to mediate HIV-1 fusion.
Richard Horuk
doaj +1 more source
Journal of Clinical & Translational Endocrinology, 2019 The term “hyperthyroidism” indicates a condition due to an exaggerate production of thyroid hormone; the most frequent cause is Graves’ disease (GD).We review cytokines and chemokines in hyperthyroidism, with a special focus in GD.In GD, recruited Th1 ...
Silvia Martina Ferrari +8 more
doaj +1 more source