Results 71 to 80 of about 78,175 (168)

Single-cell multi-omics elucidates the role of RPS27-RPS24 fusion gene in osteosarcoma chemoresistance and metabolic regulation

Cell Death Discovery
Osteosarcoma (OS) presents significant treatment challenges due to chemoresistance. This study explores the molecular mechanisms underlying chemoresistance in OS, focusing on the novel fusion gene RPS27-RPS24. Using single-cell multi-omics techniques, we
Zhiwei Tao, Pingan Zou, Zhengxu Yang, Tao Xiong, Zhi Deng, Qincan Chen   +5 more
doaj   +1 more source

The role of NAD⁺ metabolic reprogramming in colorectal cancer chemoresistance: mechanistic insights, clinical translation challenges and opportunities. [PDF]

Front Oncol
Ma Z, Gong X, Liu F.
europepmc   +1 more source

Chemotherapy induces an IL1β-dependent neutrophil recruitment and activation that promote chemoresistance in metastatic ovarian cancer. [PDF]

J Immunother Cancer
Miyamoto T, Ye Y, Soliman MM, Manning BS, Murphy B, Zhu L, Shao C, Mirji G, Minakuchi M, Hamada K, Mizuno R, Taki M, Yamanoi K, Murakami R, Mandai M, Ye Y, Wickramasinghe J, Nefedova Y, Shinde R, Kossenkov A, Zhang N.   +20 more
europepmc   +1 more source

Extracellular vesicles as regulators of chemotherapy resistance in oral squamous cell carcinoma. [PDF]

Discov Oncol
Pan S, Zhang C.
europepmc   +1 more source

Overcoming chemoresistance in esophageal cancer with synergistic strategies. [PDF]

Front Immunol
Gao C, Zhang T, Li G, Zhang W, Chen H, Li D, Xu J, Li M, Wang R, Xing Y, Zhan J, Ren Z, Xue X, Liang W, Sun X, Zhang X, Liang X, Zhan H, Zhang Z, Chu X.   +19 more
europepmc   +1 more source

Overcoming chemoresistance [PDF]

Nature Reviews Drug Discovery, 2019
openaire   +1 more source

Chemoresistance in gynecologic cancers: mechanistic insights and emerging platforms to overcome drug failure. [PDF]

J Ovarian Res
Garg P, Salgia R, Singhal SS.
europepmc   +1 more source

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway. [PDF]

Oncol Rep
Shu X, Liu H, Zhen R, Jie Y, Chen L, Qi H, Wang C, Wang R, Chen D, Ran Y.   +9 more
europepmc   +1 more source

Refining the Predictive Role of T2-Weighted Imaging Features in Breast Cancer: A Hypothesis Linking Tumor Characteristics to Extreme Chemoresistance. [PDF]

Korean J Radiol
Cao J, Tan Y, Zhang L, Gu C, Yang H, Zhang L.   +5 more
europepmc   +1 more source

Cholesterol Reprograms Oxysterol Metabolism via the LOX1/CH25H/CYP7B1 Signaling Axis to Drive Multidrug Resistance in Colorectal Cancer. [PDF]

Hum Mutat
Cheng H, Huang L, Huang J, Feng J, Huang K, Liu M, Li J.   +6 more
europepmc   +1 more source