Results 61 to 70 of about 3,719 (149)
ChIPseq libraries preparation v1
ChIP-seq was performed to analyze H3K27ac and H3K27me3 in CTRL and EZH2KO UN-KC6141 cells. Cells were crosslinked, lysed, and sonicated. Chromatin was immunoprecipitated using specific antibodies and Protein G Dynabeads. Libraries were prepared on beads using the NEBNext Ultra II kit, PCR-amplified, size-selected (200–500 bp), and sequenced on HiSeq ...
Laura Antonucci +3 more
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Advanced Science, Volume 12, Issue 33, September 4, 2025.The SNP rs2863002 at the 11p11.2 locus, identified through GWAS, is associated with an increased risk of neuroblastoma. The rs2863002‐C allele impairs the binding of the transcription factor GATA3, resulting in upregulation of the HSD17B12 gene.
Teresa Maiorino +20 more
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Emerging roles for integrated stress response signaling in homeostasis
The FEBS Journal, Volume 292, Issue 17, Page 4418-4445, September 2025.Integrated stress response (ISR), an evolutionarily conserved eukaryotic stress‐adaptive program in eukaryotes, has also been implicated in homeostatic functions. This review covers a broad body of literature and presents several homeostatic functions of ISR in the absence of stress: (a) developmental processes (morphogenesis, differentiation, aging), (
Shyama Nandakumar +2 more
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In silico pooling of ChIP-seq control experiments.
PLoS ONE, 2014 As next generation sequencing technologies are becoming more economical, large-scale ChIP-seq studies are enabling the investigation of the roles of transcription factor binding and epigenome on phenotypic variation.
Guannan Sun +5 more
doaj +1 more source
The FASEB Journal, Volume 39, Issue 15, 15 August 2025.Simultaneous deletion of TBL1 and TBLR1 in brown adipocytes leads to reduced expression of PRDM16 target genes, associated with impaired adaptive thermogenesis and defective BAT remodeling during prolonged cold exposure. While TBLR1 loss alone has minimal effects, the double knockout disrupts cold‐induced energy expenditure and promotes BAT whitening ...
Sahika Cingir Köker +25 more
wiley +1 more source
Identifying differential transcription factor binding in ChIP-seq
Frontiers in Genetics, 2015 ChIP seq is a widely used assay to measure genome-wide protein binding. The decrease in costs associated with sequencing has led to a rise in the number of studies that investigate protein binding across treatment conditions or cell lines. In addition to
Dai-Ying eWu +3 more
doaj +1 more source
A survey of models for inference of gene regulatory networks
Nonlinear Analysis, 2013 In this article, I present the biological backgrounds of microarray, ChIP-chip and ChIPSeq technologies and the application of computational methods in reverse engineering of gene regulatory networks (GRNs).
Blagoj Ristevski
doaj
, 2019 Figure S1. Schematic comparison of the ChIPmentation and high-throughput ChIPmentation protocols. Figure S2. High-throughput ChIPmentation (HT-CM) samples maintain library quality over progressively lower input cell numbers. Figure S3. High-throughput ChIPmentation (HT-CM) maintains high library complexity in CTCF samples. Table S1.
Gustafsson, Charlotte +3 more
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Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
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Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.Abstract The heterogeneity of Alzheimer's disease (AD) is multi‐dimensional, encompassing clinical features such as neuropsychiatric symptoms (NPS), rate of progression, age of onset, comorbidities, and neuropathological features such as co‐pathologies, and represents the diverse outcomes of manifold genetic and environmental risk determinants.
E. Keats Shwab +21 more
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