Role of the Cation-Chloride-Cotransporters in Cardiovascular Disease [PDF]
Cells, 2020 The SLC12 family of cation-chloride-cotransporters (CCCs) is comprised of potassium chloride cotransporters (KCCs), which mediate Cl− extrusion and sodium-potassium chloride cotransporters (N[K]CCs), which mediate Cl− loading.
Nur Farah Meor Azlan, Jinwei Zhang
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Star players sidelined in chloride homeostasis in neurons [PDF]
Frontiers in Cellular Neuroscience, 2014 The chloride ion (Cl−) is the most abundant physiological anion and is involved in many cellular functions including intracellular membrane trafficking, volume control, and excitability, as well regulating short- and long-term plasticity in neurons (Woodin et al., 2003; De Koninck, 2007; Raimondo et al., 2012; Succol et al., 2012; Stauber and Jentsch ...
Chang-Hoon eCho
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Chloride transport and homeostasis in plants
Quantitative Plant BiologyThe micronutrient chloride (Cl―) plays key roles in plant physiology, from photosystem II and vacuolar ATPase activity to osmoregulation, turgor maintenance and drought resilience, while also posing toxicity risks at high concentrations.
Harverth Silva-Herrera +5 more
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Imaging Chloride Homeostasis in Neurons [PDF]
, 2017 Intracellular chloride and pH are fundamental regulators of neuronal excitability and they are often co-modulated during excitation-inhibition activity.
Arosio, Daniele
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Early establishment of chloride homeostasis in CRH neurons is altered by prenatal stress leading to fetal HPA axis dysregulation [PDF]
Frontiers in Molecular NeuroscienceCorticotropin-releasing hormone (CRH) neurons play an important role in the regulation of neuroendocrine responses to stress. The excitability of CRH neurons is regulated by inhibitory GABAergic inputs. However, it is unclear when GABAergic regulation of
Miho Watanabe +3 more
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Chloride Homeostasis in Central Neurons
, 2016 The overall aim of the present thesis is to clarify the control of intracellular chloride homeostasis in central neurons, because of the critical role of chloride ions (Cl–) for neuronal function.
Yelhekar, Tushar
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Chloride Homeostasis in Neurons With Special Emphasis on the Olivocerebellar System: Differential Roles for Transporters and Channels [PDF]
Frontiers in Cellular Neuroscience, 2018 The intraneuronal ionic composition is an important determinant of brain functioning. There is growing evidence that aberrant homeostasis of the intracellular concentration of Cl− ([Cl−]i) evokes, in addition to that of Na+ and Ca2+, robust impairments ...
Negah Rahmati +5 more
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Leptin down-regulates KCC2 activity and controls chloride homeostasis in the neonatal rat hippocampus [PDF]
Molecular Brain, 2020 The canonical physiological role of leptin is to regulate hunger and satiety acting on specific hypothalamic nuclei. Beyond this key metabolic function; leptin also regulates many aspects of development and functioning of neuronal hippocampal networks ...
Camille Dumon +5 more
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Chloride homeostasis dysfunction drives hyperactivation of corticotropin-releasing factor-expressing neurons in the amygdala in stress-induced hypertension [PDF]
The Journal of Clinical InvestigationStress promotes the progression from borderline hypertension to sustained hypertension, but the mechanism remains unclear. We investigated the role of corticotropin-releasing factor (CRF)-expressing neurons in the central nucleus of amygdala (CeA) on ...
Hongyu Ma +8 more
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Nitrate-chloride interactions: a molecular model of chloride homeostasis regulation
Resumen de la comunicación oral presentada en II ANDALUCÍA AGRO-HUB PhD students Meeting 11-12 marzo 2025 Estación Experimental del Zaidín, GranadaThe growing need to increase agricultural production in today's world competes with the negative effects of
Colmenero Flores, José M. +4 more
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