Results 11 to 20 of about 731,089 (287)
Enhanced chondrocyte culture and growth on biologically inspired nanofibrous cell culture dishes
International Journal of Nanomedicine, 2016 Garima Bhardwaj,1 Thomas J Webster1,2 1Department of Chemical Engineering, Northeastern University, Boston, MA, USA; 2Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah, Saudi Arabia Abstract: Chondral and ...
Bhardwaj G, Webster TJ
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Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice. [PDF]
Int J Mol Sci, 2020 Runx2 is required for chondrocyte proliferation and maturation. In the search of Runx2 target genes in chondrocytes, we found that Runx2 up-regulated the expression of hematopoietic cell kinase (Hck), which is a member of the Src tyrosine kinase family ...
Matsuura VKSK +6 more
europepmc +2 more sources
Chondrocyte proliferation in a new culture system [PDF]
Cell Proliferation, 2009 AbstractObjective: This study has aimed to study different culture systems that might stimulate an increase in cell proliferation of normal and osteoarthritis chondrocytes from articular cartilage in rat model.Material and Methods: Three culture systems using chondrocytes embedded in alginate beads were tested: chondrocytes cultured in Dulbecco's ...
M A, Gomez-Camarillo +4 more
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Characterisation of human mesenchymal stem cell metabolism during proliferation and differentiation. [PDF]
, 2010 PhDMesenchymal stem cells (MSCs) have the ability to differentiate towards cartilage, bone, fat and muscle, and therefore have great therapeutic potential.
Pattappa, Girish
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Arthritis Research & Therapy, 2023 Background Osteoarthritis (OA) is a degenerative disease related to cholesterol metabolism disorders. However, current therapies for OA are insufficient and no convincing disease-modifying OA drugs exist. Therefore, we aimed to elucidate the mechanism by
WeiBing Wang +9 more
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Journal of Orthopaedic Surgery and Research, 2021 Background Osteoarthritis (OA) is a joint disease characterized via destruction of cartilage. Chondrocyte damage is associated with cartilage destruction during OA.
Jipeng Lu, Zhongxiong Wu, Ying Xiong
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Journal of Orthopaedic Surgery and Research, 2022 Background This study aimed to analyze the in vitro effect of micro-strain stress on the proliferation and functional marker expression in chondrocytes isolated from human osteoarthritis cartilage samples.
Bin Zhao +3 more
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Adipose-Derived Stem Cells Cocultured with Chondrocytes Promote the Proliferation of Chondrocytes [PDF]
Stem Cells International, 2017 Articular cartilage injury and defect caused by trauma and chronic osteoarthritis vascularity are very common, while the repair of injured cartilage remains a great challenge due to its limited healing capacity. Stem cell-based tissue engineering provides a promising treatment option for injured articular cartilage because of the cells potential for ...
Jie Shi +6 more
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Journal of Nanobiotechnology, 2021 Background Extracellular vesicles (EVs) secreted by mesenchymal stem cells (MSCs) may play a vital role in a variety of biological processes, including cartilage regeneration.
Shenglong Li +4 more
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miR-29b inhibits TGF-β1-induced cell proliferation in articular chondrocytes
Biochemistry and Biophysics Reports, 2022 Transforming growth factor β1 (TGF-β1) is a known regulator of chondrocyte proliferation and promotes cartilage repair in osteoarthritis (OA). microRNA-29b-3p (miR-29b-3p) is downregulated by TGF-β1 and overexpressed in OA cartilage. However, the ability
Masahiro Horita +4 more
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