Results 1 to 10 of about 1,033,685 (362)
Mechanical Mechanisms of Chromosome Segregation [PDF]
Cells, 2021 Chromosome segregation—the partitioning of genetic material into two daughter cells—is one of the most crucial processes in cell division. In all Eukaryotes, chromosome segregation is driven by the spindle, a microtubule-based, self-organizing ...
Maya I. Anjur-Dietrich +2 more
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Coordination of Chromosome Segregation and Cell Division in Staphylococcus aureus [PDF]
Frontiers in Microbiology, 2017 Productive bacterial cell division and survival of progeny requires tight coordination between chromosome segregation and cell division to ensure equal partitioning of DNA.
Amy L. Bottomley +6 more
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Chromosome segregation in plant meiosis [PDF]
Frontiers in Plant Science, 2014 Faithful chromosome segregation in meiosis is essential for ploidy stability over sexual life cycles. In plants, defective chromosome segregation caused by gene mutations or other factors leads to the formation of unbalanced or unreduced gametes creating
Linda eZamariola +4 more
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Bacterial chromosome segregation by the ParABS system [PDF]
Open Biology, 2020 Proper chromosome segregation during cell division is essential in all domains of life. In the majority of bacterial species, faithful chromosome segregation is mediated by the tripartite ParABS system, consisting of an ATPase protein ParA, a CTPase and ...
Adam S. B. Jalal, Tung B. K. Le
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Chromosome Segregation Is Biased by Kinetochore Size [PDF]
Current Biology, 2018 Chromosome missegregation during mitosis or meiosis is a hallmark of cancer and the main cause of prenatal death in humans. The gain or loss of specific chromosomes is thought to be random, with cell viability being essentially determined by selection ...
Danica Drpic +8 more
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The coordination of nuclear envelope assembly and chromosome segregation in metazoans
Nucleus, 2020 The nuclear envelope (NE) is composed of two lipid bilayer membranes that enclose the eukaryotic genome. In interphase, the NE is perforated by thousands of nuclear pore complexes (NPCs), which allow transport in and out of the nucleus. During mitosis in
Shiwei Liu, David Pellman
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Exotic mitotic mechanisms [PDF]
Open Biology, 2012 The emergence of eukaryotes around two billion years ago provided new challenges for the chromosome segregation machineries: the physical separation of multiple large and linear chromosomes from the microtubule-organizing centres by the nuclear envelope.
Hauke Drechsler, Andrew D. McAinsh
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Centromere-localized Aurora B kinase is required for the fidelity of chromosome segregation [PDF]
Journal of Cell Biology, 2019 Aurora B localizes to centromeres, but it is unclear if this influences chromosome segregation in mitosis. Liang et al. find that two phospho-histone marks separately recruit Aurora B to centromeres and act redundantly for faithful chromosome segregation.
Liang Cai +8 more
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mBio, 2012 Vibrio cholerae has two chromosomes (chrI and chrII) whose replication and segregation are under different genetic controls. The region covering the replication origin of chrI resembles that of the Escherichia coli chromosome, and both origins are under ...
Ryosuke Kadoya, Dhruba K. Chattoraj
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NuSAP4 regulates chromosome segregation in Trypanosoma brucei by promoting bipolar spindle assembly [PDF]
Communications BiologyFaithful chromosome segregation in eukaryotes requires the assembly of a bipolar spindle and the faithful attachment of kinetochores to spindle microtubules, which are regulated by various spindle-associated proteins (SAPs) that play distinct functions ...
Qing Zhou, Ziyin Li
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