Results 1 to 10 of about 995,917 (290)
Mechanical Mechanisms of Chromosome Segregation [PDF]
Cells, 2021 Chromosome segregation—the partitioning of genetic material into two daughter cells—is one of the most crucial processes in cell division. In all Eukaryotes, chromosome segregation is driven by the spindle, a microtubule-based, self-organizing ...
Maya I. Anjur-Dietrich +2 more
doaj +5 more sources
Chromosome segregation in plant meiosis [PDF]
Frontiers in Plant Science, 2014 Faithful chromosome segregation in meiosis is essential for ploidy stability over sexual life cycles. In plants, defective chromosome segregation caused by gene mutations or other factors leads to the formation of unbalanced or unreduced gametes creating
Linda eZamariola +4 more
doaj +10 more sources
Coordination of Chromosome Segregation and Cell Division in Staphylococcus aureus [PDF]
Frontiers in Microbiology, 2017 Productive bacterial cell division and survival of progeny requires tight coordination between chromosome segregation and cell division to ensure equal partitioning of DNA.
Amy L. Bottomley +6 more
doaj +6 more sources
Spo0J and SMC are required for normal chromosome segregation in Staphylococcus aureus [PDF]
MicrobiologyOpen, 2020 Bacterial chromosome segregation is an essential cellular process that is particularly elusive in spherical bacteria such as the opportunistic human pathogen Staphylococcus aureus.
Helena Chan +2 more
doaj +5 more sources
Evolutionary dynamics of adult stem cells: Comparison of random and immortal strand segregation mechanisms [PDF]
, 2004 This paper develops a point-mutation model describing the evolutionary dynamics of a population of adult stem cells. Such a model may prove useful for quantitative studies of tissue aging and the emergence of cancer. We consider two modes of chromosome segregation: (1) Random segregation, where the daughter chromosomes of a given parent chromosome ...
A. T. Natarajan +4 more
arxiv +3 more sources
Chromosome Segregation Is Biased by Kinetochore Size [PDF]
Current Biology, 2018 Chromosome missegregation during mitosis or meiosis is a hallmark of cancer and the main cause of prenatal death in humans. The gain or loss of specific chromosomes is thought to be random, with cell viability being essentially determined by selection ...
Danica Drpic +8 more
semanticscholar +3 more sources
Bacterial chromosome segregation by the ParABS system [PDF]
Open Biology, 2020 Proper chromosome segregation during cell division is essential in all domains of life. In the majority of bacterial species, faithful chromosome segregation is mediated by the tripartite ParABS system, consisting of an ATPase protein ParA, a CTPase and ...
Adam S. B. Jalal, Tung B. K. Le
doaj +2 more sources
Double-checking chromosome segregation. [PDF]
J Cell Biol, 2023 Enduring chromosome segregation errors represent potential threats to genomic stability due to eventual chromosome copy number alterations (aneuploidy) and formation of micronuclei—key intermediates of a rapid mutational process known as chromothripsis that is found in cancer and congenital disorders.
Maiato H, Silva S.
europepmc +3 more sources
The coordination of nuclear envelope assembly and chromosome segregation in metazoans
Nucleus, 2020 The nuclear envelope (NE) is composed of two lipid bilayer membranes that enclose the eukaryotic genome. In interphase, the NE is perforated by thousands of nuclear pore complexes (NPCs), which allow transport in and out of the nucleus. During mitosis in
Shiwei Liu, David Pellman
doaj +2 more sources
Time scale of entropic segregation of flexible polymers in confinement: Implications for chromosome segregation in filamentous bacteria [PDF]
A. Arnold and S. Jun, Phys. Rev. E 76, 031901 (2007), 2007 We report molecular dynamics simulations of the segregation of two overlapping chains in cylindrical confinement. We find that the entropic repulsion between the chains can be sufficiently strong to cause segregation on a time scale that is short compared to the one for diffusion. This result implies that entropic driving forces are sufficiently strong
Axel Arnold +4 more
arxiv +3 more sources