Results 131 to 140 of about 52,173 (326)

Crosstalk between m6A mRNAs and m6A circRNAs and the time-specific biogenesis of m6A circRNAs after OGD/R in primary neurons

Epigenetics, 2023
Cerebral ischaemiareperfusion injury is an important pathological process in nervous system diseases during which neurons undergo oxygenglucose deprivation and reoxygenation (OGD/R) injury.
Chi Zhang, Huan Jian, Shenghui Shang, Lu Lu, Yongfu Lou, Yi Kang, Hong Bai, Zheng Fu, Yigang Lv, Xiaohong Kong, Xueying Li, Shiqing Feng, Hengxing Zhou   +12 more
doaj   +1 more source

Genome-Wide Profiling of Circular RNAs in the Rapidly Growing Shoots of Moso Bamboo (Phyllostachys edulis). [PDF]

, 2019
Circular RNAs, including circular exonic RNAs (circRNA), circular intronic RNAs (ciRNA) and exon-intron circRNAs (EIciRNAs), are a new type of noncoding RNAs.
Gao, Yubang, Gu, Lianfeng, Hu, Kaiqiang, Kohnen, Markus V, Lin, Chentao, Liu, Xuqing, Wang, Huihui, Wang, Huiyuan, Wang, Yongsheng, Xi, Feihu, Xu, Xi, Zhang, Hangxiao, Zhang, Zeyu, Zhao, Liangzhen   +13 more
core  

Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification [PDF]

, 2020
Understanding genome organization and gene regulation requires insight into RNA transcription, processing and modification. We adapted nanopore direct RNA sequencing to examine RNA from a wild-type accession of the model plant Arabidopsis thaliana and a ...
Barton, Geoffrey J., Gould, Peter D., Hall, Anthony J. W., Knop, Katarzyna, Mackinnon, Katarzyna, Parker, Matthew T., Schurch, Nicholas J., Sherwood, Anna V., Simpson, Gordon G.   +8 more
core   +3 more sources

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

Animal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou, Huajun Wang, Hao Guo, Dongbin Luo, Xiaofei Zheng, Simin Luo   +5 more
wiley   +1 more source

Dysregulation of circRNA-0076906 and circRNA-0134944 is Correlated with Susceptibility to Osteoporosis and Osteoporotic Fracture in Postmenopausal Females from the Chinese Han Population

Pharmacogenomics and Personalized Medicine, 2023
Weijie Yang,* Wei Zhang,* Fengqian Li, Ning Xu, Ping Sun Department of Orthopedics, Shanghai Eighth People’s Hospital, Shanghai, 200235, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ping Sun ...
Yang W, Zhang W, Li F, Xu N, Sun P
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Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt

Annals of Neurology, EarlyView.
As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez, Cyril Pottier, Aleksandra Beric, Daniel Western, Muhammad Ali, Carlos Cruchaga   +5 more
wiley   +1 more source

Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles [PDF]

, 2019
RNA profiling has emerged as a powerful tool to investigate the biomarker potential of human biofluids. However, despite enormous interest in extracellular nucleic acids, RNA sequencing methods to quantify the total RNA content outside cells are rare ...
Anckaert, Jasper, Decock, Anneleen, Dhondt, Bert, Everaert, Celine, Helsmoortel, Hetty, Hendrix, An, Hulstaert, Eva, Mestdagh, Pieter, Nijs, Nele, Nuytens, Justine, Tulkens, Joeri, Van Paemel, Ruben, Vandesompele, Jo, Verniers, Kimberly   +13 more
core   +1 more source

Astragaloside IV exhibits anti-tumor function in gastric cancer via targeting circRNA dihydrolipoamide S-succinyltransferase (circDLST)/miR-489-3p/ eukaryotic translation initiation factor 4A1(EIF4A1) pathway [PDF]

, 2022
Fagen Li, Ke Cao, Maoyun Wang, Yi Liu, Yin Zhang   +4 more
openalex   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Recent Update on the Role of Circular RNAs in Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2021
Abdullah Ely, Kristie Bloom, Mohube Betty Maepa, Patrick Arbuthnot Wits/SAMRC Antiviral Gene Therapy Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaCorrespondence: Patrick ...
Ely A, Bloom K, Maepa MB, Arbuthnot P
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