Results 121 to 130 of about 24,361 (224)

CircRNAs in the heart: bricks in Brunelleschi’s Dome [PDF]

Cardiovascular Research, 2020
Paula A da Costa Martins, Federica De Majo   +1 more
openaire   +3 more sources

Microfluidic nanochips for rapid exosome isolation and multiplex biomarker profiling from a single blood drop: Toward sample‐to‐answer liquid biopsy

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
A microfluidic nanodevice that analyses a single volume droplet of whole blood (10–50 microlitres (µL)) forms a fast and fully integrated exosome‐derived liquid biopsy. The closed system architecture involves plasma separation on chip, exosome enrichment by immunoaffinity and various size based, electrokinetic, acoustofluidic or hybridized strategies ...
Daniel Ejim Uti, Esther Ugo Alum, Josephine E. Egbung, Waheeb Sami Aggad, Hailah M. Almohaimeed, Zuhair M. Mohammedsaleh, Manpreet Kaur, Kranti Kiran Reddy Ealla   +7 more
wiley   +1 more source

The evolving landscape of the Warburg effect in gastric cancer: From molecular mechanisms to targeted therapy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu, Pan Li, Zizhuo Li, Jie Li, Chenggang Zhang, Yihua Wang, Weiming Kang, Xin Ye   +7 more
wiley   +1 more source

Comprehensive analysis of differentially expressed circRNAs revealed a ceRNA network in pancreatic ductaladenocarcinoma

Archives of Medical Science, 2019
Jin-Zhe Zhou, Mu-Ren Hu, Hong-Liang Diao, Qi-Wei Wang, Qi Huang, Bu-Jun Ge   +5 more
doaj   +1 more source

Extracellular Vesicles in Acute Myeloid Leukemia: Opportunities and Obstacles for Therapeutic Advancement

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Acute myeloid leukemia (AML) is a disease characterized by uncontrolled proliferation and blocked maturation of hematopoietic stem and progenitor cells. Despite progress in its clinical management, many patients continue to relapse or show limited response to standard therapies, emphasizing the need for novel, safe, and more effective targeted ...
Rongrong Hu, Zaker Ataullev, Luping Lou
wiley   +1 more source

m6A‐methylated circFANCB Promotes Gastric Cancer Progression by Regulating Cellular Ferroptosis Through miR‐454‐3p/CEACAM5

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
This study reveals that METTL3 regulates circFANCB expression by inducing m6A modification. CircFANCB modulates cellular ferroptosis by regulating the miR‐454‐3p/CEACAM5 axis, thereby promoting the growth and metastasis of gastric cancer cells. ABSTRACT Gastric cancer (GC) is a major global digestive malignancy with high incidence and mortality ...
Haifeng Wang, Yan Li, Tiantian Sun, Man Su, Wei Dai, Zhihui Jin, Hangchen Shen, Changyu Jin, Yan Gao   +8 more
wiley   +1 more source

Hsa_circ_0044097 Serves as a Promising Biomarker of Atherosclerosis and Its Effects on Vascular Smooth Cell Proliferation and Migration

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Hsa_circ_0044097 expression level was decreased AS patients and in ox‐LDL‐HASMC. The expression level of hsa_circ_0044097 is negatively correlated with the levels of hs‐CRP and LDL‐C. Hsa_circ_0044097 can be a biomarker for the diagnosis and prediction of MACE.
Cencen Ren, Yungen Jiao
wiley   +1 more source

Transcriptomic Convergence in Autism Spectrum Disorder: Synaptic, Immune‐Glial and RNA‐Regulatory Axes in the Human Cerebral Cortex

International Journal of Developmental Neuroscience, Volume 86, Issue 5, August 2026.
Across 43 human post‐mortem cortical transcriptomic studies, ASD shows recurrent but non‐uniform convergence on reduced synaptic‐neuronal signalling, increased immune‐glial activity and RNA‐regulatory dysregulation. Metabolic and mitochondrial changes are less consistently supported and appear more conditional within the current cortical evidence base.
Ruslan Kurmashev
wiley   +1 more source

Reprogramming Glial Cell Metabolism via a tRNA Fragment Preserves Vision in Retinal Neurodegeneration

MedComm, Volume 7, Issue 8, August 2026.
Under oxidative and excitotoxic stress, Müller cell‐derived 5′tiRNA‐His‐GTG contributes to retinal neurodegeneration. Pathological stimuli increase ANG‐dependent production of 5′tiRNA‐His‐GTG, which suppresses LPCAT1 expression and disrupts phosphatidylcholine (PC)‐mediated glycerophospholipid metabolism.
Yuke Ji, Sha Liu, Ying Zhang, Junya Zhu, Chang Huang, Ya Zhao, Jiao Xia, Wan Mu, Jin Yao, Biao Yan   +9 more
wiley   +1 more source

Circ_0008146 Exacerbates Ferroptosis via Regulating the miR-342-5p/ACSL4 Axis After Cerebral Ischemic/Reperfusion

Journal of Inflammation Research
Cai-Dong Liu,1,2,* Qiang Peng,3,* Shi-Yao Wang,3,* Yang Deng,2 Zhong-Yuan Li,3 Zhao-Han Xu,3 Liang Wu,3 Ying-Dong Zhang,2,3 Rui Duan3 1Department of Laboratory Medicine, Nanjing First Hospital, China Pharmaceutical University, Nanjing ...
Liu CD, Peng Q, Wang SY, Deng Y, Li ZY, Xu ZH, Wu L, Zhang YD, Duan R   +8 more
doaj